ADVANCED GENOME EDITING

Methods of genetically modifying microorganisms using advanced genome editing are disclosed. Methods of modifying the genome of these microorganisms for point mutations, deletions, and DNA insertions are also disclosed. Further, inhibiting expression of genes without manipulating the genome of the m...

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Hauptverfasser: LI, Xuezhi, KEALEY, James, DIETZEL, Kevin Lee
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KEALEY, James
DIETZEL, Kevin Lee
description Methods of genetically modifying microorganisms using advanced genome editing are disclosed. Methods of modifying the genome of these microorganisms for point mutations, deletions, and DNA insertions are also disclosed. Further, inhibiting expression of genes without manipulating the genome of the microorganism is disclosed. In some cases, the microorganism can be a methylotroph, e.g., a methanotroph. L'invention concerne des procédés de modification génétique de micro-organismes à l'aide d'une édition de génome évoluée. Des procédés de modification du génome desdits micro-organismes en termes de mutations ponctuelles, délétions et insertions d'ADN sont décrits. De plus, l'inhibition de l'expression de gènes sans manipulation du génome du micro-organisme sont en outre décrits. Dans certains cas, le micro-organisme peut être un méthylotrophe, p. ex., un méthanotrophe.
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Methods of modifying the genome of these microorganisms for point mutations, deletions, and DNA insertions are also disclosed. Further, inhibiting expression of genes without manipulating the genome of the microorganism is disclosed. In some cases, the microorganism can be a methylotroph, e.g., a methanotroph. L'invention concerne des procédés de modification génétique de micro-organismes à l'aide d'une édition de génome évoluée. Des procédés de modification du génome desdits micro-organismes en termes de mutations ponctuelles, délétions et insertions d'ADN sont décrits. De plus, l'inhibition de l'expression de gènes sans manipulation du génome du micro-organisme sont en outre décrits. 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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title ADVANCED GENOME EDITING
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