SYNTHESIS METHODS OF FIROCOXIB AND INTERMEDIATE THEREOF

Provided herein the synthesis methods of firocoxib and an intermediate thereof. The synthesis of the first intermediate is performed through methylation of p-bromopropiophenone or through Friedel-Crafts acylation of bromobenzene, avoiding the use of environmental unfriendly thioethers as starting ma...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	WANG, Ying, LU, Tiegang, LI, Xiaoxun, LIU, Shikui, DENG, Xianhua
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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