COACERVATE PRODUCTION METHOD USING COACERVATION AND THE USAGE OF COACERVATES OBTAINED BY THIS METHOD AS TISSUE SCAFFOLD
The present invention relates to production of tissue scaffolds, which are capable of cell encapsulation (macro-encapsulation) for tissue engineering using complex coacervation technique, with chitosan (CT) and hyaluronic acid (HA) polymers. The objective of the present invention is to provide a met...
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| creator | KAYITMAZER BÜYÜKOKUTAN, Ayşe Başak KARABIYIK ACAR, Özge TORUN KOSE, Gamze |
| description | The present invention relates to production of tissue scaffolds, which are capable of cell encapsulation (macro-encapsulation) for tissue engineering using complex coacervation technique, with chitosan (CT) and hyaluronic acid (HA) polymers. The objective of the present invention is to provide a method for producing tissue scaffolds; which consist of entirely natural polymers that are biodegradable, biocompatible and have elastic feature, and are non-toxic since no crosslinking agents or organic solvents are used; and which have a porous structure providing a suitable environment for cell viability and proliferation, and also for differentiation if stem cell will be used
La présente invention concerne la production d'échafaudages tissulaires qui sont capables d'encapsulation cellulaire (macro-encapsulation) pour l'ingénierie tissulaire au moyen d'une technique de coacervation complexe, avec du chitosane (CT) et des polymères d'acide hyaluronique (HA). L'objectif de la présente invention est de proposer un procédé de production d'échafaudages tissulaires qui comprennent des polymères entièrement naturels qui sont biodégradables, biocompatibles et présentent une caractéristique élastique et ne sont pas toxiques, puisqu'aucun agent de réticulation ou solvant organique n'est utilisé, et qui ont une structure poreuse fournissant un environnement adéquat pour la viabilité et la prolifération cellulaires et également pour la différenciation cellulaire en cas d'utilisation de cellules souches. |
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La présente invention concerne la production d'échafaudages tissulaires qui sont capables d'encapsulation cellulaire (macro-encapsulation) pour l'ingénierie tissulaire au moyen d'une technique de coacervation complexe, avec du chitosane (CT) et des polymères d'acide hyaluronique (HA). L'objectif de la présente invention est de proposer un procédé de production d'échafaudages tissulaires qui comprennent des polymères entièrement naturels qui sont biodégradables, biocompatibles et présentent une caractéristique élastique et ne sont pas toxiques, puisqu'aucun agent de réticulation ou solvant organique n'est utilisé, et qui ont une structure poreuse fournissant un environnement adéquat pour la viabilité et la prolifération cellulaires et également pour la différenciation cellulaire en cas d'utilisation de cellules souches.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190613&DB=EPODOC&CC=WO&NR=2019054971A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190613&DB=EPODOC&CC=WO&NR=2019054971A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KAYITMAZER BÜYÜKOKUTAN, Ayşe Başak</creatorcontrib><creatorcontrib>KARABIYIK ACAR, Özge</creatorcontrib><creatorcontrib>TORUN KOSE, Gamze</creatorcontrib><title>COACERVATE PRODUCTION METHOD USING COACERVATION AND THE USAGE OF COACERVATES OBTAINED BY THIS METHOD AS TISSUE SCAFFOLD</title><description>The present invention relates to production of tissue scaffolds, which are capable of cell encapsulation (macro-encapsulation) for tissue engineering using complex coacervation technique, with chitosan (CT) and hyaluronic acid (HA) polymers. The objective of the present invention is to provide a method for producing tissue scaffolds; which consist of entirely natural polymers that are biodegradable, biocompatible and have elastic feature, and are non-toxic since no crosslinking agents or organic solvents are used; and which have a porous structure providing a suitable environment for cell viability and proliferation, and also for differentiation if stem cell will be used
La présente invention concerne la production d'échafaudages tissulaires qui sont capables d'encapsulation cellulaire (macro-encapsulation) pour l'ingénierie tissulaire au moyen d'une technique de coacervation complexe, avec du chitosane (CT) et des polymères d'acide hyaluronique (HA). 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La présente invention concerne la production d'échafaudages tissulaires qui sont capables d'encapsulation cellulaire (macro-encapsulation) pour l'ingénierie tissulaire au moyen d'une technique de coacervation complexe, avec du chitosane (CT) et des polymères d'acide hyaluronique (HA). L'objectif de la présente invention est de proposer un procédé de production d'échafaudages tissulaires qui comprennent des polymères entièrement naturels qui sont biodégradables, biocompatibles et présentent une caractéristique élastique et ne sont pas toxiques, puisqu'aucun agent de réticulation ou solvant organique n'est utilisé, et qui ont une structure poreuse fournissant un environnement adéquat pour la viabilité et la prolifération cellulaires et également pour la différenciation cellulaire en cas d'utilisation de cellules souches.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ENZYMOLOGY HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | COACERVATE PRODUCTION METHOD USING COACERVATION AND THE USAGE OF COACERVATES OBTAINED BY THIS METHOD AS TISSUE SCAFFOLD |
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