TREATMENT OF INFLAMMATORY CONDITIONS AND AUTOIMMUNE DISEASES WITH GLUCOSE UPTAKE INHIBITORS
This invention provides methods of treating inflammatory conditions and autoimmune diseases in a mammal, comprising administering to the mammalian subject in need thereof a therapeutically effective amount of a compound, or pro-drug thereof, or pharmaceutically acceptable salt or ester of said compo...
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| creator | BARSOTTI, Anthony POYUROVSKY, Masha OLSZEWSKI, Kellen MORRIS, Koi KIM, Ji-ln LIU, Kevin YU, Xuemei |
| description | This invention provides methods of treating inflammatory conditions and autoimmune diseases in a mammal, comprising administering to the mammalian subject in need thereof a therapeutically effective amount of a compound, or pro-drug thereof, or pharmaceutically acceptable salt or ester of said compound or pro-drug, wherein the compound is an inhibitor of glucose uptake. In particular aspects, the present invention provides a method of treating inflammatory conditions and autoimmune diseases in a mammal, and preferably a human, in which the glucose uptake inhibitor modulates the glucose transport of GLUTl and GLUT3.
La présente invention concerne des procédés de traitement d'affections inflammatoires et de maladies auto-immunes chez un mammifère, comprenant l'administration au sujet mammifère en ayant besoin d'une quantité thérapeutiquement efficace d'un composé, ou un promédicament de celui-ci, ou un sel ou ester pharmaceutiquement acceptable dudit composé ou promédicament, le composé étant un inhibiteur de l'absorption du glucose. Dans des aspects particuliers, la présente invention concerne un procédé de traitement d'affections inflammatoires et de maladies auto-immunes chez un mammifère et, de préférence, un humain, dans lequel l'inhibiteur d'absorption de glucose module le transport de glucose de GLUTl et GLUT3. |
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La présente invention concerne des procédés de traitement d'affections inflammatoires et de maladies auto-immunes chez un mammifère, comprenant l'administration au sujet mammifère en ayant besoin d'une quantité thérapeutiquement efficace d'un composé, ou un promédicament de celui-ci, ou un sel ou ester pharmaceutiquement acceptable dudit composé ou promédicament, le composé étant un inhibiteur de l'absorption du glucose. Dans des aspects particuliers, la présente invention concerne un procédé de traitement d'affections inflammatoires et de maladies auto-immunes chez un mammifère et, de préférence, un humain, dans lequel l'inhibiteur d'absorption de glucose module le transport de glucose de GLUTl et GLUT3.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20181101&DB=EPODOC&CC=WO&NR=2018201006A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20181101&DB=EPODOC&CC=WO&NR=2018201006A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BARSOTTI, Anthony</creatorcontrib><creatorcontrib>POYUROVSKY, Masha</creatorcontrib><creatorcontrib>OLSZEWSKI, Kellen</creatorcontrib><creatorcontrib>MORRIS, Koi</creatorcontrib><creatorcontrib>KIM, Ji-ln</creatorcontrib><creatorcontrib>LIU, Kevin</creatorcontrib><creatorcontrib>YU, Xuemei</creatorcontrib><title>TREATMENT OF INFLAMMATORY CONDITIONS AND AUTOIMMUNE DISEASES WITH GLUCOSE UPTAKE INHIBITORS</title><description>This invention provides methods of treating inflammatory conditions and autoimmune diseases in a mammal, comprising administering to the mammalian subject in need thereof a therapeutically effective amount of a compound, or pro-drug thereof, or pharmaceutically acceptable salt or ester of said compound or pro-drug, wherein the compound is an inhibitor of glucose uptake. In particular aspects, the present invention provides a method of treating inflammatory conditions and autoimmune diseases in a mammal, and preferably a human, in which the glucose uptake inhibitor modulates the glucose transport of GLUTl and GLUT3.
La présente invention concerne des procédés de traitement d'affections inflammatoires et de maladies auto-immunes chez un mammifère, comprenant l'administration au sujet mammifère en ayant besoin d'une quantité thérapeutiquement efficace d'un composé, ou un promédicament de celui-ci, ou un sel ou ester pharmaceutiquement acceptable dudit composé ou promédicament, le composé étant un inhibiteur de l'absorption du glucose. Dans des aspects particuliers, la présente invention concerne un procédé de traitement d'affections inflammatoires et de maladies auto-immunes chez un mammifère et, de préférence, un humain, dans lequel l'inhibiteur d'absorption de glucose module le transport de glucose de GLUTl et GLUT3.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjDEKwkAQAK-xEPUPC9ZCoiC2a7LxFnO3ktsjiEUIclaigfh_TOEDLIZphpmbmzaE6sgrSAXsqxqdQ5XmCoX4kpXFB0BfAkYVdi56gpIDYaAALauFUx0LCQTxonim6WH5yNMhLM3s0T_HtPp5YdYVaWE3aXh3aRz6e3qlT9fKNssPE1m2x3z3X_UFk0szaw</recordid><startdate>20181101</startdate><enddate>20181101</enddate><creator>BARSOTTI, Anthony</creator><creator>POYUROVSKY, Masha</creator><creator>OLSZEWSKI, Kellen</creator><creator>MORRIS, Koi</creator><creator>KIM, Ji-ln</creator><creator>LIU, Kevin</creator><creator>YU, Xuemei</creator><scope>EVB</scope></search><sort><creationdate>20181101</creationdate><title>TREATMENT OF INFLAMMATORY CONDITIONS AND AUTOIMMUNE DISEASES WITH GLUCOSE UPTAKE INHIBITORS</title><author>BARSOTTI, Anthony ; POYUROVSKY, Masha ; OLSZEWSKI, Kellen ; MORRIS, Koi ; KIM, Ji-ln ; LIU, Kevin ; YU, Xuemei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2018201006A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2018</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>BARSOTTI, Anthony</creatorcontrib><creatorcontrib>POYUROVSKY, Masha</creatorcontrib><creatorcontrib>OLSZEWSKI, Kellen</creatorcontrib><creatorcontrib>MORRIS, Koi</creatorcontrib><creatorcontrib>KIM, Ji-ln</creatorcontrib><creatorcontrib>LIU, Kevin</creatorcontrib><creatorcontrib>YU, Xuemei</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BARSOTTI, Anthony</au><au>POYUROVSKY, Masha</au><au>OLSZEWSKI, Kellen</au><au>MORRIS, Koi</au><au>KIM, Ji-ln</au><au>LIU, Kevin</au><au>YU, Xuemei</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TREATMENT OF INFLAMMATORY CONDITIONS AND AUTOIMMUNE DISEASES WITH GLUCOSE UPTAKE INHIBITORS</title><date>2018-11-01</date><risdate>2018</risdate><abstract>This invention provides methods of treating inflammatory conditions and autoimmune diseases in a mammal, comprising administering to the mammalian subject in need thereof a therapeutically effective amount of a compound, or pro-drug thereof, or pharmaceutically acceptable salt or ester of said compound or pro-drug, wherein the compound is an inhibitor of glucose uptake. In particular aspects, the present invention provides a method of treating inflammatory conditions and autoimmune diseases in a mammal, and preferably a human, in which the glucose uptake inhibitor modulates the glucose transport of GLUTl and GLUT3.
La présente invention concerne des procédés de traitement d'affections inflammatoires et de maladies auto-immunes chez un mammifère, comprenant l'administration au sujet mammifère en ayant besoin d'une quantité thérapeutiquement efficace d'un composé, ou un promédicament de celui-ci, ou un sel ou ester pharmaceutiquement acceptable dudit composé ou promédicament, le composé étant un inhibiteur de l'absorption du glucose. Dans des aspects particuliers, la présente invention concerne un procédé de traitement d'affections inflammatoires et de maladies auto-immunes chez un mammifère et, de préférence, un humain, dans lequel l'inhibiteur d'absorption de glucose module le transport de glucose de GLUTl et GLUT3.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | TREATMENT OF INFLAMMATORY CONDITIONS AND AUTOIMMUNE DISEASES WITH GLUCOSE UPTAKE INHIBITORS |
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