METHODS AND MICROORGANISMS FOR THE FERMENTATION OF METHANE TO MULTI-CARBON COMPOUNDS

Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as isobutanol are disclosed. For example, genetically modified methanotrophs that are capable of generating isobutanol at high titers from a methane source are disclosed. Methods of mak...

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Bibliographische Detailangaben
Hauptverfasser:	ZHAO, Xinhua, WAWRZYN, Grayson Thomas, LI, Xuezhi, SCHMALISCH, Matthias Helmut, HELD, Mark Anton, FARWELL, Christopher Cheney, CLARK, Louis A, CHAO, Lily Yuin, TRINH, Na My, ORTH, Jeffrey David, DIETZEL, Kevin Lee, KEALEY, James
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as isobutanol are disclosed. For example, genetically modified methanotrophs that are capable of generating isobutanol at high titers from a methane source are disclosed. Methods of making these genetically modified microorganisms and methods of using them are also disclosed. L'invention concerne des micro-organismes génétiquement modifiés aptes à convertir des substrats carbonés en produits chimiques tels que l'isobutanol. L'invention concerne par exemple des méthanotrophes génétiquement modifiés, aptes à générer de l'isobutanol à des titres élevés à partir d'une source de méthane. L'invention concerne également des procédés de fabrication de ces micro-organismes génétiquement modifiés, ainsi que des procédés d'utilisation associés.