METHOD FOR PRODUCING 5-(3,6-DIHYDRO-2,6-DIOXO-4-TRIFLUOROMETHYL-1(2H)-PYRIMIDINYL)PHENYLTHIOL COMPOUND
The present invention relates to a method for producing a 5-(3,6-dihydro-2,6-dioxo-4-trifluoromethyl-1(2H)-pyrimidinyl)phenylthiol compound. The production method according to the present invention enables provision of stable yield and safety of production process by suppressing the runaway reaction...
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| creator | KUK, Jinchul LEE, Junwon LEE, Kyungjae AHN, Youngchun |
| description | The present invention relates to a method for producing a 5-(3,6-dihydro-2,6-dioxo-4-trifluoromethyl-1(2H)-pyrimidinyl)phenylthiol compound. The production method according to the present invention enables provision of stable yield and safety of production process by suppressing the runaway reaction by controlling the reaction rate when synthesizing a 5-(3,6-dihydro-2,6-dioxo-4-trifluoromethyl-1(2H)pyrimidinyl)phenylthiol compound.
La présente invention concerne un procédé de production d'un composé de 5-(3,6-dihydro-2,6-dioxo-4-trifluorométhyl-1(2H)-pyrimidinyl)phénylthiol. Le procédé de production selon la présente invention permet de fournir un rendement et une sécurité stables du processus de production en supprimant la réaction d'emballement en régulant le taux de réaction lors de la synthèse d'un composé 5-(3,6-dihydro-2,6-dioxo-4-trifluorométhyl-1(2H)pyrimidinyl)phénylthiol.
본 발명은 5-(3,6-다이하이드로-2,6-다이옥소-4-트리플루오로메틸-1(2H)-피리미디닐)페닐싸이올 화합물의 제조 방법에 관한 것이다. 본 발명에 따른 제조 방법은 5-(3,6-다이하이드로-2,6-다이옥소-4-트리플루오로메틸-1(2H)-피리미디닐)페닐싸이올 화합물의 합성시 반응 속도의 제어를 통해 폭주 반응을 억제함으로써 제조 공정의 안전성과 안정된 수율의 확보를 가능케 한다. |
| format | Patent |
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La présente invention concerne un procédé de production d'un composé de 5-(3,6-dihydro-2,6-dioxo-4-trifluorométhyl-1(2H)-pyrimidinyl)phénylthiol. Le procédé de production selon la présente invention permet de fournir un rendement et une sécurité stables du processus de production en supprimant la réaction d'emballement en régulant le taux de réaction lors de la synthèse d'un composé 5-(3,6-dihydro-2,6-dioxo-4-trifluorométhyl-1(2H)pyrimidinyl)phénylthiol.
본 발명은 5-(3,6-다이하이드로-2,6-다이옥소-4-트리플루오로메틸-1(2H)-피리미디닐)페닐싸이올 화합물의 제조 방법에 관한 것이다. 본 발명에 따른 제조 방법은 5-(3,6-다이하이드로-2,6-다이옥소-4-트리플루오로메틸-1(2H)-피리미디닐)페닐싸이올 화합물의 합성시 반응 속도의 제어를 통해 폭주 반응을 억제함으로써 제조 공정의 안전성과 안정된 수율의 확보를 가능케 한다.</description><language>eng ; fre ; kor</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180712&DB=EPODOC&CC=WO&NR=2018128390A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25544,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180712&DB=EPODOC&CC=WO&NR=2018128390A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KUK, Jinchul</creatorcontrib><creatorcontrib>LEE, Junwon</creatorcontrib><creatorcontrib>LEE, Kyungjae</creatorcontrib><creatorcontrib>AHN, Youngchun</creatorcontrib><title>METHOD FOR PRODUCING 5-(3,6-DIHYDRO-2,6-DIOXO-4-TRIFLUOROMETHYL-1(2H)-PYRIMIDINYL)PHENYLTHIOL COMPOUND</title><description>The present invention relates to a method for producing a 5-(3,6-dihydro-2,6-dioxo-4-trifluoromethyl-1(2H)-pyrimidinyl)phenylthiol compound. The production method according to the present invention enables provision of stable yield and safety of production process by suppressing the runaway reaction by controlling the reaction rate when synthesizing a 5-(3,6-dihydro-2,6-dioxo-4-trifluoromethyl-1(2H)pyrimidinyl)phenylthiol compound.
La présente invention concerne un procédé de production d'un composé de 5-(3,6-dihydro-2,6-dioxo-4-trifluorométhyl-1(2H)-pyrimidinyl)phénylthiol. Le procédé de production selon la présente invention permet de fournir un rendement et une sécurité stables du processus de production en supprimant la réaction d'emballement en régulant le taux de réaction lors de la synthèse d'un composé 5-(3,6-dihydro-2,6-dioxo-4-trifluorométhyl-1(2H)pyrimidinyl)phénylthiol.
본 발명은 5-(3,6-다이하이드로-2,6-다이옥소-4-트리플루오로메틸-1(2H)-피리미디닐)페닐싸이올 화합물의 제조 방법에 관한 것이다. 본 발명에 따른 제조 방법은 5-(3,6-다이하이드로-2,6-다이옥소-4-트리플루오로메틸-1(2H)-피리미디닐)페닐싸이올 화합물의 합성시 반응 속도의 제어를 통해 폭주 반응을 억제함으로써 제조 공정의 안전성과 안정된 수율의 확보를 가능케 한다.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNi7sKwjAUQLs4iPoPAZcWvNCkKnWUpjUX0t4QUjRTKZJOooX6__jAD3A6ZzhnHg116RRJVpFlxpJsC2xObAdxttmDROWlJRBfpwvBFpzFSrdk6TN6DTwWKgHjLdYosfE6Map8wykkzQqqDbWNXEazob9NYfXjIlpXpSsUhPHRhWnsr-Eent2ZRMpzLvLskB559l_1AjE6NZk</recordid><startdate>20180712</startdate><enddate>20180712</enddate><creator>KUK, Jinchul</creator><creator>LEE, Junwon</creator><creator>LEE, Kyungjae</creator><creator>AHN, Youngchun</creator><scope>EVB</scope></search><sort><creationdate>20180712</creationdate><title>METHOD FOR PRODUCING 5-(3,6-DIHYDRO-2,6-DIOXO-4-TRIFLUOROMETHYL-1(2H)-PYRIMIDINYL)PHENYLTHIOL COMPOUND</title><author>KUK, Jinchul ; LEE, Junwon ; LEE, Kyungjae ; AHN, Youngchun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2018128390A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; kor</language><creationdate>2018</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>KUK, Jinchul</creatorcontrib><creatorcontrib>LEE, Junwon</creatorcontrib><creatorcontrib>LEE, Kyungjae</creatorcontrib><creatorcontrib>AHN, Youngchun</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KUK, Jinchul</au><au>LEE, Junwon</au><au>LEE, Kyungjae</au><au>AHN, Youngchun</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD FOR PRODUCING 5-(3,6-DIHYDRO-2,6-DIOXO-4-TRIFLUOROMETHYL-1(2H)-PYRIMIDINYL)PHENYLTHIOL COMPOUND</title><date>2018-07-12</date><risdate>2018</risdate><abstract>The present invention relates to a method for producing a 5-(3,6-dihydro-2,6-dioxo-4-trifluoromethyl-1(2H)-pyrimidinyl)phenylthiol compound. The production method according to the present invention enables provision of stable yield and safety of production process by suppressing the runaway reaction by controlling the reaction rate when synthesizing a 5-(3,6-dihydro-2,6-dioxo-4-trifluoromethyl-1(2H)pyrimidinyl)phenylthiol compound.
La présente invention concerne un procédé de production d'un composé de 5-(3,6-dihydro-2,6-dioxo-4-trifluorométhyl-1(2H)-pyrimidinyl)phénylthiol. Le procédé de production selon la présente invention permet de fournir un rendement et une sécurité stables du processus de production en supprimant la réaction d'emballement en régulant le taux de réaction lors de la synthèse d'un composé 5-(3,6-dihydro-2,6-dioxo-4-trifluorométhyl-1(2H)pyrimidinyl)phénylthiol.
본 발명은 5-(3,6-다이하이드로-2,6-다이옥소-4-트리플루오로메틸-1(2H)-피리미디닐)페닐싸이올 화합물의 제조 방법에 관한 것이다. 본 발명에 따른 제조 방법은 5-(3,6-다이하이드로-2,6-다이옥소-4-트리플루오로메틸-1(2H)-피리미디닐)페닐싸이올 화합물의 합성시 반응 속도의 제어를 통해 폭주 반응을 억제함으로써 제조 공정의 안전성과 안정된 수율의 확보를 가능케 한다.</abstract><oa>free_for_read</oa></addata></record> |
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| title | METHOD FOR PRODUCING 5-(3,6-DIHYDRO-2,6-DIOXO-4-TRIFLUOROMETHYL-1(2H)-PYRIMIDINYL)PHENYLTHIOL COMPOUND |
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