MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS AND USES THEREOF

The present invention relates generally to chemical compounds and methods for their use and preparation in relation to the treatment of diseases, disorders or conditions which would benefit from the modulation of the alpha 7 nicotinic acetylcholine receptor (α7 nAChR). The invention thus also relate...

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Hauptverfasser: CONTRERAS, Jean-Marie, MORICE, Christophe, STAHL, Cindy, MITCHELL, Lorna Helen, FEICHTER, Nicolas, SCHAEFFER, Laurent, HARVEY, Andrew John, BAZZINI, Patrick, RIPPER, Justin Anthony
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creator CONTRERAS, Jean-Marie
MORICE, Christophe
STAHL, Cindy
MITCHELL, Lorna Helen
FEICHTER, Nicolas
SCHAEFFER, Laurent
HARVEY, Andrew John
BAZZINI, Patrick
RIPPER, Justin Anthony
description The present invention relates generally to chemical compounds and methods for their use and preparation in relation to the treatment of diseases, disorders or conditions which would benefit from the modulation of the alpha 7 nicotinic acetylcholine receptor (α7 nAChR). The invention thus also relates to the use of these compounds in methods of therapy and the manufacture of medicaments as well as compositions containing these compounds. La présente invention concerne de manière générale des composés chimiques et des procédés pour leur utilisation et leur préparation en relation avec le traitement de maladies, de troubles ou d'états pathologiques qui bénéficieraient de la modulation du récepteur nicotinique de l'acétylcholine alpha 7 (α7 nAChR). L'invention concerne également l'utilisation de ces composés dans des procédés thérapeutiques ainsi que dans la fabrication de médicaments et des compositions contenant ces composés.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS AND USES THEREOF
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