PHARMACEUTICAL COMPOSITION COMPRISING AMORPHOUS SELEXIPAG

The present invention is directed to solid state forms of selexipag (Formula (I)), including an amorphous form of selexipag and a selexipag-containing premix, to methods for their preparation, to pharmaceutical compositions comprising them and to their use in medicine, particularly for the treatment...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	MALHOTRA, Geena, PUPPALA, Ravikumar, GANGRADE, Manish Gopaldas, PATHI, Srinivas Laxminarayan, RAO, Dharmaraj Ramachandra, KOMMULA, Narayanaswami, RANKIREDDI, Anand Ramesh
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention is directed to solid state forms of selexipag (Formula (I)), including an amorphous form of selexipag and a selexipag-containing premix, to methods for their preparation, to pharmaceutical compositions comprising them and to their use in medicine, particularly for the treatment of pulmonary arterial hypertension. (Formula (I)) La présente invention concerne des formes à l'état solide de selexipag (formule (I)), comprenant une forme amorphe du selexipag et un pré-mélange contenant du selexipag, des méthodes pour leur préparation, des compositions pharmaceutiques les comprenant et leur utilisation en médecine, en particulier pour le traitement de l'hypertension artérielle pulmonaire. (Formule (I))