PEPTIDE INHIBITORS OF SODIUM CHANNELS
The present invention relates to the ability of specialized non-naturally occurring peptides to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to mo...
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| creator | TAYLOR, John, Clayton CHRISTENSEN, Dale, J CROWDER, Timothy, Morgan |
| description | The present invention relates to the ability of specialized non-naturally occurring peptides to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of specialized non-naturally occurring peptides to sodium channels.
La présente invention concerne la capacité de peptides spécialisés d'origine non naturelle à se lier à des canaux sodiques et à inhiber l'activation desdits canaux sodiques. L'invention concerne, en outre, des méthodes de régulation de l'absorption du sodium et d'un volume de fluide, ainsi que de traitement de troubles sensibles à la modulation de l'absorption du sodium par modulation de la liaison de peptides spécialisés d'origine non naturelle aux canaux sodiques. |
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La présente invention concerne la capacité de peptides spécialisés d'origine non naturelle à se lier à des canaux sodiques et à inhiber l'activation desdits canaux sodiques. L'invention concerne, en outre, des méthodes de régulation de l'absorption du sodium et d'un volume de fluide, ainsi que de traitement de troubles sensibles à la modulation de l'absorption du sodium par modulation de la liaison de peptides spécialisés d'origine non naturelle aux canaux sodiques.</description><language>eng ; fre</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180405&DB=EPODOC&CC=WO&NR=2018064499A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76419</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180405&DB=EPODOC&CC=WO&NR=2018064499A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TAYLOR, John, Clayton</creatorcontrib><creatorcontrib>CHRISTENSEN, Dale, J</creatorcontrib><creatorcontrib>CROWDER, Timothy, Morgan</creatorcontrib><title>PEPTIDE INHIBITORS OF SODIUM CHANNELS</title><description>The present invention relates to the ability of specialized non-naturally occurring peptides to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of specialized non-naturally occurring peptides to sodium channels.
La présente invention concerne la capacité de peptides spécialisés d'origine non naturelle à se lier à des canaux sodiques et à inhiber l'activation desdits canaux sodiques. L'invention concerne, en outre, des méthodes de régulation de l'absorption du sodium et d'un volume de fluide, ainsi que de traitement de troubles sensibles à la modulation de l'absorption du sodium par modulation de la liaison de peptides spécialisés d'origine non naturelle aux canaux sodiques.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFANcA0I8XRxVfD08_B08gzxDwpW8HdTCPZ38Qz1VXD2cPTzc_UJ5mFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8eH-RgaGFgZmJiaWlo6GxsSpAgAwXiRK</recordid><startdate>20180405</startdate><enddate>20180405</enddate><creator>TAYLOR, John, Clayton</creator><creator>CHRISTENSEN, Dale, J</creator><creator>CROWDER, Timothy, Morgan</creator><scope>EVB</scope></search><sort><creationdate>20180405</creationdate><title>PEPTIDE INHIBITORS OF SODIUM CHANNELS</title><author>TAYLOR, John, Clayton ; CHRISTENSEN, Dale, J ; CROWDER, Timothy, Morgan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2018064499A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2018</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>TAYLOR, John, Clayton</creatorcontrib><creatorcontrib>CHRISTENSEN, Dale, J</creatorcontrib><creatorcontrib>CROWDER, Timothy, Morgan</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TAYLOR, John, Clayton</au><au>CHRISTENSEN, Dale, J</au><au>CROWDER, Timothy, Morgan</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PEPTIDE INHIBITORS OF SODIUM CHANNELS</title><date>2018-04-05</date><risdate>2018</risdate><abstract>The present invention relates to the ability of specialized non-naturally occurring peptides to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of specialized non-naturally occurring peptides to sodium channels.
La présente invention concerne la capacité de peptides spécialisés d'origine non naturelle à se lier à des canaux sodiques et à inhiber l'activation desdits canaux sodiques. L'invention concerne, en outre, des méthodes de régulation de l'absorption du sodium et d'un volume de fluide, ainsi que de traitement de troubles sensibles à la modulation de l'absorption du sodium par modulation de la liaison de peptides spécialisés d'origine non naturelle aux canaux sodiques.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | PEPTIDE INHIBITORS OF SODIUM CHANNELS |
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