ADENOVIRUS ARMED WITH BISPECIFIC T CELL ENGAGER (BITE)

A modified adenovirus, in particular Enadenotucirev (EnAd), armed with a bispecific T cell engager (BiTE) comprising at least two binding domains, wherein at least one of the domains is specific for a surface antigen on a T-cell of interest. Also provided are a composition, such as a pharmaceutical...

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Hauptverfasser: BROWN, Alice, Claire, Noel, FREEDMAN, Joshua, David, FISHER, Kerry, David, CHAMPION, Brian, Robert, SEYMOUR, Leonard, William
Format: Patent
Sprache:eng ; fre
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