COMPOSITIONS AND METHODS FOR MUSCLE PROGENITOR CELL-BASED THERAPIES

Disclosed herein are methods and compositions that provide for improved production and efficacy of cell-based therapies. For example, the culture of muscle progenitor cells (satellite cells) on laminin 521 is provided as a means to maintain differentiation and engraftment potential of the cells, e.g...

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Bibliographische Detailangaben
Hauptverfasser:	PENTON, Christopher M, AUGUST, Paul
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Disclosed herein are methods and compositions that provide for improved production and efficacy of cell-based therapies. For example, the culture of muscle progenitor cells (satellite cells) on laminin 521 is provided as a means to maintain differentiation and engraftment potential of the cells, e.g. for therapeutic purposes. L'invention concerne des procédés et des compositions qui permettent une production et une efficacité accrues des traitements à base de cellules. Par exemple, la culture de cellules progénitrices musculaires (cellules satellites) sur de la laminine 521 est utilisée en tant que moyen pour le maintien du potentiel de différenciation et de prise de greffe des cellules, par exemple à des fins thérapeutiques.