INDUCED PLURIPOTENT STEM CELL CULTURE PLATE USING NANOTOPOGRAPHY AND CULTURING METHOD USING SAME

The present invention relates to an induced pluripotent stem cell culture plate and, more particularly, to an induced pluripotent stem cell culture plate which enables acquisition of a large amount of induced pluripotent stem cells, having maintained stemness and excellent proliferation and adhesion properties, by means of a culture membrane, which is a reproduction of the influence of the extracellular matrix by means of nanotopography and has a plurality of prominent parts and depressed parts aligned and forming a pattern, and a modifier which coats the surface of the culture membrane and thus enhances the adhesion properties. La présente invention concerne une plaque de culture de cellules souches pluripotentes induites et, plus particulièrement, une plaque de culture de cellules souches pluripotentes induites qui permet l'acquisition d'une grande quantité de cellules souches pluripotentes induites, ayant une souchitude conservée et d'excellentes propriétés de prolifération et d'adhérence, au moyen d'une membrane de culture, qui reproduit l'influence de la matrice extracellulaire au moyen de la nanotopographie et qui comporte une pluralité de parties saillantes et de parties en creux alignées et formant un motif, et un modificateur qui recouvre la surface de la membrane de culture et améliore ainsi les propriétés d'adhérence. 본 발명은 유도만능줄기세포 배양 플레이트에 관한 것으로서, 보다 구체적으로는, 세포외기질의 영향을 나노지형 (nanotopography)을 이용하여 재현하는 철부 및 요부가 복수개로 배열되어 패턴을 형성한 배양 멤브레인 및 상기 배양 멤브레인 표면에 코팅되어 부착능을 향상시키는 개질제를 통해 줄기세포성이 유지되면서, 증식 및 부착 능력이 우수한 유도만능줄기세포를 다량으로 획득할 수 있는, 유도만능줄기세포 배양 플레이트에 관한 것이다.