SYNERGISTIC TUMOR TREATMENT WITH IL-2, AN INTEGRIN-BINDING-FC FUSION PROTEIN, AND A CANCER VACCINNE

The present invention provides a method of treating cancer with a combination of IL-2 (e.g., extended-PK IL-2), an integrin-binding-Fc fusion protein, and a cancer vaccine. The methods of the invention can be used to treat a broad range of cancer types. La présente invention concerne un procédé de t...

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Hauptverfasser: WITTRUP, Karl Dane, OPEL, Cary Francis, KWAN, Byron Hua, COCHRAN, Jennifer R, MOYNIHAN, Kelly Dare, IRVINE, Darrell J
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creator WITTRUP, Karl Dane
OPEL, Cary Francis
KWAN, Byron Hua
COCHRAN, Jennifer R
MOYNIHAN, Kelly Dare
IRVINE, Darrell J
description The present invention provides a method of treating cancer with a combination of IL-2 (e.g., extended-PK IL-2), an integrin-binding-Fc fusion protein, and a cancer vaccine. The methods of the invention can be used to treat a broad range of cancer types. La présente invention concerne un procédé de traitement du cancer à l'aide d'une combinaison d'IL-2 (par exemple, IL-2 à pharmacocinétique prolongée), d'une protéine de fusion Fc liant l'intégrine, et d'un vaccin contre le cancer. Les procédés de l'invention peuvent être utilisé pour traiter un large éventail de types de cancer.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title SYNERGISTIC TUMOR TREATMENT WITH IL-2, AN INTEGRIN-BINDING-FC FUSION PROTEIN, AND A CANCER VACCINNE
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