USE OF STATIN-BASED DRUG FOR TREATMENT OF EML4-ALK-POSITIVE NON-SMALL CELL LUNG CANCER RESISTANT TO ALK INHIBITOR
Provided according to the present invention is a pharmaceutical composition exhibiting therapeutic efficacy against EML4-ALK-positive non-small cell lung cancer that has acquired resistance to an ALK inhibitor. Also, provided is information for drug selection on the basis of which the administration...
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| creator | PYO, Kyoung-Ho KANG, Han Na CHO, Kyoung-Je YOON, Mi-Ran CHOI, Hun-Mi CHO, Byoung Chul |
| description | Provided according to the present invention is a pharmaceutical composition exhibiting therapeutic efficacy against EML4-ALK-positive non-small cell lung cancer that has acquired resistance to an ALK inhibitor. Also, provided is information for drug selection on the basis of which the administration of statin-based drugs to a patient group with EML4-ALK-positive non-small cell lung cancer can be determined.
La présente invention concerne une composition pharmaceutique présentant une efficacité thérapeutique contre un cancer pulmonaire non à petites cellules positif à l'EML4-ALK qui a acquis une résistance à un inhibiteur de l'ALK. L'invention concerne également des informations de sélection de médicaments à partir desquelles peut être déterminée l'administration des médicaments à base de statine à un groupe de patients atteints d'un cancer pulmonaire non à petites cellules positif à l'EML4-ALK.
본 발명의 약제학적 조성물은 ALK 저해제에 대한 내성을 획득한 EML4-ALK 양성 비소세포폐암에 치료 효능을 나타내는 약제학적 조성물을 제공할 수 있다. 또한, EML4-ALK 양성 비소세포폐암 환자군에 있어서, 스타틴계 약물의 투여 여부를 결정하기 위한 약물 선택을 위한 정보를 제공할 수 있다. |
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La présente invention concerne une composition pharmaceutique présentant une efficacité thérapeutique contre un cancer pulmonaire non à petites cellules positif à l'EML4-ALK qui a acquis une résistance à un inhibiteur de l'ALK. L'invention concerne également des informations de sélection de médicaments à partir desquelles peut être déterminée l'administration des médicaments à base de statine à un groupe de patients atteints d'un cancer pulmonaire non à petites cellules positif à l'EML4-ALK.
본 발명의 약제학적 조성물은 ALK 저해제에 대한 내성을 획득한 EML4-ALK 양성 비소세포폐암에 치료 효능을 나타내는 약제학적 조성물을 제공할 수 있다. 또한, EML4-ALK 양성 비소세포폐암 환자군에 있어서, 스타틴계 약물의 투여 여부를 결정하기 위한 약물 선택을 위한 정보를 제공할 수 있다.</description><language>eng ; fre ; kor</language><subject>HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEDICAL OR VETERINARY SCIENCE ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; TESTING</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170720&DB=EPODOC&CC=WO&NR=2017123063A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170720&DB=EPODOC&CC=WO&NR=2017123063A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PYO, Kyoung-Ho</creatorcontrib><creatorcontrib>KANG, Han Na</creatorcontrib><creatorcontrib>CHO, Kyoung-Je</creatorcontrib><creatorcontrib>YOON, Mi-Ran</creatorcontrib><creatorcontrib>CHOI, Hun-Mi</creatorcontrib><creatorcontrib>CHO, Byoung Chul</creatorcontrib><title>USE OF STATIN-BASED DRUG FOR TREATMENT OF EML4-ALK-POSITIVE NON-SMALL CELL LUNG CANCER RESISTANT TO ALK INHIBITOR</title><description>Provided according to the present invention is a pharmaceutical composition exhibiting therapeutic efficacy against EML4-ALK-positive non-small cell lung cancer that has acquired resistance to an ALK inhibitor. Also, provided is information for drug selection on the basis of which the administration of statin-based drugs to a patient group with EML4-ALK-positive non-small cell lung cancer can be determined.
La présente invention concerne une composition pharmaceutique présentant une efficacité thérapeutique contre un cancer pulmonaire non à petites cellules positif à l'EML4-ALK qui a acquis une résistance à un inhibiteur de l'ALK. L'invention concerne également des informations de sélection de médicaments à partir desquelles peut être déterminée l'administration des médicaments à base de statine à un groupe de patients atteints d'un cancer pulmonaire non à petites cellules positif à l'EML4-ALK.
본 발명의 약제학적 조성물은 ALK 저해제에 대한 내성을 획득한 EML4-ALK 양성 비소세포폐암에 치료 효능을 나타내는 약제학적 조성물을 제공할 수 있다. 또한, EML4-ALK 양성 비소세포폐암 환자군에 있어서, 스타틴계 약물의 투여 여부를 결정하기 위한 약물 선택을 위한 정보를 제공할 수 있다.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PHYSICS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjL0KwjAURrs4iPoOF5wD_RGd0_S2Daa5ktzqWIrESbRS3x8j-AAu31nO-ZbJq_cIVINnydqKUnqsoHJ9AzU5YIeSO7T8VbAzOyHNUZzIa9ZnBEtW-E4aAwrjmN42oKRV6MCh1_EzlkwQI9C21aVmcutkcRvvc9j8uEq2NbJqRZieQ5in8Roe4T1cKE-zQ5YX6b6QWfGf9QGkIjiH</recordid><startdate>20170720</startdate><enddate>20170720</enddate><creator>PYO, Kyoung-Ho</creator><creator>KANG, Han Na</creator><creator>CHO, Kyoung-Je</creator><creator>YOON, Mi-Ran</creator><creator>CHOI, Hun-Mi</creator><creator>CHO, Byoung Chul</creator><scope>EVB</scope></search><sort><creationdate>20170720</creationdate><title>USE OF STATIN-BASED DRUG FOR TREATMENT OF EML4-ALK-POSITIVE NON-SMALL CELL LUNG CANCER RESISTANT TO ALK INHIBITOR</title><author>PYO, Kyoung-Ho ; KANG, Han Na ; CHO, Kyoung-Je ; YOON, Mi-Ran ; CHOI, Hun-Mi ; CHO, Byoung Chul</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2017123063A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; kor</language><creationdate>2017</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PHYSICS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>PYO, Kyoung-Ho</creatorcontrib><creatorcontrib>KANG, Han Na</creatorcontrib><creatorcontrib>CHO, Kyoung-Je</creatorcontrib><creatorcontrib>YOON, Mi-Ran</creatorcontrib><creatorcontrib>CHOI, Hun-Mi</creatorcontrib><creatorcontrib>CHO, Byoung Chul</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PYO, Kyoung-Ho</au><au>KANG, Han Na</au><au>CHO, Kyoung-Je</au><au>YOON, Mi-Ran</au><au>CHOI, Hun-Mi</au><au>CHO, Byoung Chul</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>USE OF STATIN-BASED DRUG FOR TREATMENT OF EML4-ALK-POSITIVE NON-SMALL CELL LUNG CANCER RESISTANT TO ALK INHIBITOR</title><date>2017-07-20</date><risdate>2017</risdate><abstract>Provided according to the present invention is a pharmaceutical composition exhibiting therapeutic efficacy against EML4-ALK-positive non-small cell lung cancer that has acquired resistance to an ALK inhibitor. Also, provided is information for drug selection on the basis of which the administration of statin-based drugs to a patient group with EML4-ALK-positive non-small cell lung cancer can be determined.
La présente invention concerne une composition pharmaceutique présentant une efficacité thérapeutique contre un cancer pulmonaire non à petites cellules positif à l'EML4-ALK qui a acquis une résistance à un inhibiteur de l'ALK. L'invention concerne également des informations de sélection de médicaments à partir desquelles peut être déterminée l'administration des médicaments à base de statine à un groupe de patients atteints d'un cancer pulmonaire non à petites cellules positif à l'EML4-ALK.
본 발명의 약제학적 조성물은 ALK 저해제에 대한 내성을 획득한 EML4-ALK 양성 비소세포폐암에 치료 효능을 나타내는 약제학적 조성물을 제공할 수 있다. 또한, EML4-ALK 양성 비소세포폐암 환자군에 있어서, 스타틴계 약물의 투여 여부를 결정하기 위한 약물 선택을 위한 정보를 제공할 수 있다.</abstract><oa>free_for_read</oa></addata></record> |
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| title | USE OF STATIN-BASED DRUG FOR TREATMENT OF EML4-ALK-POSITIVE NON-SMALL CELL LUNG CANCER RESISTANT TO ALK INHIBITOR |
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