PYRAZINE COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC PROTOZOAL INFECTIONS
The present invention relates to compounds of Formula (I) having pharmacological activity, processes for its preparation, pharmaceutical compositions and their use in the treatment of certain parasitic certain parasiticprotozoalinfections such as malaria, in particular infection by Plasmodium falcip...
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creator | GARCIA MARTIN, Mercedes CASTELLOTE ALVARO, Maria Isabel |
description | The present invention relates to compounds of Formula (I) having pharmacological activity, processes for its preparation, pharmaceutical compositions and their use in the treatment of certain parasitic certain parasiticprotozoalinfections such as malaria, in particular infection by Plasmodium falciparum. Formula (I), wherein R is methyl or fluoro.
La présente invention concerne des composés de formule (I) présentant une activité pharmacologique, des procédés pour leur préparation, des compositions pharmaceutiques et leur utilisation dans le traitement de certaines infections causées par des protozoaires parasites telles que la malaria, en particulier une infection par Plasmodium falciparum. Formule (I), dans laquelle R est un méthyle ou un fluoro. |
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La présente invention concerne des composés de formule (I) présentant une activité pharmacologique, des procédés pour leur préparation, des compositions pharmaceutiques et leur utilisation dans le traitement de certaines infections causées par des protozoaires parasites telles que la malaria, en particulier une infection par Plasmodium falciparum. Formule (I), dans laquelle R est un méthyle ou un fluoro.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170427&DB=EPODOC&CC=WO&NR=2017067881A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170427&DB=EPODOC&CC=WO&NR=2017067881A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GARCIA MARTIN, Mercedes</creatorcontrib><creatorcontrib>CASTELLOTE ALVARO, Maria Isabel</creatorcontrib><title>PYRAZINE COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC PROTOZOAL INFECTIONS</title><description>The present invention relates to compounds of Formula (I) having pharmacological activity, processes for its preparation, pharmaceutical compositions and their use in the treatment of certain parasitic certain parasiticprotozoalinfections such as malaria, in particular infection by Plasmodium falciparum. Formula (I), wherein R is methyl or fluoro.
La présente invention concerne des composés de formule (I) présentant une activité pharmacologique, des procédés pour leur préparation, des compositions pharmaceutiques et leur utilisation dans le traitement de certaines infections causées par des protozoaires parasites telles que la malaria, en particulier une infection par Plasmodium falciparum. Formule (I), dans laquelle R est un méthyle ou un fluoro.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAQANAsDqL-w4Gz0CjYrke80IDJheSK2KUUiZNoof4_OvgBTm95S-XjNWHvAoFhH7kLpwyWE3SZwAWQlkASoXgKAmwhYsLsxBmIiYV7xvP3WTLiOOS1WtzHx1w2P1dqa0lMuyvTayjzNN7Ks7yHC-8rXVfHumk06sN_6wPOkS-P</recordid><startdate>20170427</startdate><enddate>20170427</enddate><creator>GARCIA MARTIN, Mercedes</creator><creator>CASTELLOTE ALVARO, Maria Isabel</creator><scope>EVB</scope></search><sort><creationdate>20170427</creationdate><title>PYRAZINE COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC PROTOZOAL INFECTIONS</title><author>GARCIA MARTIN, Mercedes ; CASTELLOTE ALVARO, Maria Isabel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2017067881A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2017</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>GARCIA MARTIN, Mercedes</creatorcontrib><creatorcontrib>CASTELLOTE ALVARO, Maria Isabel</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GARCIA MARTIN, Mercedes</au><au>CASTELLOTE ALVARO, Maria Isabel</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PYRAZINE COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC PROTOZOAL INFECTIONS</title><date>2017-04-27</date><risdate>2017</risdate><abstract>The present invention relates to compounds of Formula (I) having pharmacological activity, processes for its preparation, pharmaceutical compositions and their use in the treatment of certain parasitic certain parasiticprotozoalinfections such as malaria, in particular infection by Plasmodium falciparum. Formula (I), wherein R is methyl or fluoro.
La présente invention concerne des composés de formule (I) présentant une activité pharmacologique, des procédés pour leur préparation, des compositions pharmaceutiques et leur utilisation dans le traitement de certaines infections causées par des protozoaires parasites telles que la malaria, en particulier une infection par Plasmodium falciparum. Formule (I), dans laquelle R est un méthyle ou un fluoro.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | PYRAZINE COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC PROTOZOAL INFECTIONS |
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