CHK1/2 INHIBITORS FOR USE IN THE TREATMENT OF NEUROBLASTOMAS AND/OR SOFT TISSUE SARCOMAS
The present invention provides 5-(5-(2-(3-aminopropoxy)-6-methoxyphenyl)-lH- pyrazol-3-ylamino)pyrazine~2~carbonitrile and pharmaceutically acceptable salts and solvates thereof, that is capable of inhibiting CHK1 and is useful in the treatment of neuroblastomas and/or soft tissue sarcomas. La prése...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | STANCATO, Louis Frank |
| description | The present invention provides 5-(5-(2-(3-aminopropoxy)-6-methoxyphenyl)-lH- pyrazol-3-ylamino)pyrazine~2~carbonitrile and pharmaceutically acceptable salts and solvates thereof, that is capable of inhibiting CHK1 and is useful in the treatment of neuroblastomas and/or soft tissue sarcomas.
La présente invention concerne un 5-(5-(2-(3-aminopropoxy)-6-méthoxyphényl)-1H-pyrazol-3-ylamino)pyrazine-2-carbonitrile, ainsi que des sels et solvates pharmaceutiquement acceptables de celui-ci, qui peut inhiber le CHK1 et est utile dans le traitement de neuroblastomes et/ou de sarcomes des tissus mous. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO2017015124A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO2017015124A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO2017015124A13</originalsourceid><addsrcrecordid>eNqNikEKwjAQAHPxIOofFjxLm6p4TuOGBG0Wslv0VorEk2ih_h8r-ABPAzMzV1frT7qoIEQf6iCUGBwlaBknBeIRJKGRBqMAOYjYJqrPhoUaw2DisZhuJicggblFYJPsty3V7N4_xrz6caHWDsX6TR5eXR6H_paf-d1dqCr1odR7Xe2M3v53fQCAnjHZ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>CHK1/2 INHIBITORS FOR USE IN THE TREATMENT OF NEUROBLASTOMAS AND/OR SOFT TISSUE SARCOMAS</title><source>esp@cenet</source><creator>STANCATO, Louis Frank</creator><creatorcontrib>STANCATO, Louis Frank</creatorcontrib><description>The present invention provides 5-(5-(2-(3-aminopropoxy)-6-methoxyphenyl)-lH- pyrazol-3-ylamino)pyrazine~2~carbonitrile and pharmaceutically acceptable salts and solvates thereof, that is capable of inhibiting CHK1 and is useful in the treatment of neuroblastomas and/or soft tissue sarcomas.
La présente invention concerne un 5-(5-(2-(3-aminopropoxy)-6-méthoxyphényl)-1H-pyrazol-3-ylamino)pyrazine-2-carbonitrile, ainsi que des sels et solvates pharmaceutiquement acceptables de celui-ci, qui peut inhiber le CHK1 et est utile dans le traitement de neuroblastomes et/ou de sarcomes des tissus mous.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170126&DB=EPODOC&CC=WO&NR=2017015124A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20170126&DB=EPODOC&CC=WO&NR=2017015124A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>STANCATO, Louis Frank</creatorcontrib><title>CHK1/2 INHIBITORS FOR USE IN THE TREATMENT OF NEUROBLASTOMAS AND/OR SOFT TISSUE SARCOMAS</title><description>The present invention provides 5-(5-(2-(3-aminopropoxy)-6-methoxyphenyl)-lH- pyrazol-3-ylamino)pyrazine~2~carbonitrile and pharmaceutically acceptable salts and solvates thereof, that is capable of inhibiting CHK1 and is useful in the treatment of neuroblastomas and/or soft tissue sarcomas.
La présente invention concerne un 5-(5-(2-(3-aminopropoxy)-6-méthoxyphényl)-1H-pyrazol-3-ylamino)pyrazine-2-carbonitrile, ainsi que des sels et solvates pharmaceutiquement acceptables de celui-ci, qui peut inhiber le CHK1 et est utile dans le traitement de neuroblastomes et/ou de sarcomes des tissus mous.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2017</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNikEKwjAQAHPxIOofFjxLm6p4TuOGBG0Wslv0VorEk2ih_h8r-ABPAzMzV1frT7qoIEQf6iCUGBwlaBknBeIRJKGRBqMAOYjYJqrPhoUaw2DisZhuJicggblFYJPsty3V7N4_xrz6caHWDsX6TR5eXR6H_paf-d1dqCr1odR7Xe2M3v53fQCAnjHZ</recordid><startdate>20170126</startdate><enddate>20170126</enddate><creator>STANCATO, Louis Frank</creator><scope>EVB</scope></search><sort><creationdate>20170126</creationdate><title>CHK1/2 INHIBITORS FOR USE IN THE TREATMENT OF NEUROBLASTOMAS AND/OR SOFT TISSUE SARCOMAS</title><author>STANCATO, Louis Frank</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2017015124A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2017</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>STANCATO, Louis Frank</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>STANCATO, Louis Frank</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CHK1/2 INHIBITORS FOR USE IN THE TREATMENT OF NEUROBLASTOMAS AND/OR SOFT TISSUE SARCOMAS</title><date>2017-01-26</date><risdate>2017</risdate><abstract>The present invention provides 5-(5-(2-(3-aminopropoxy)-6-methoxyphenyl)-lH- pyrazol-3-ylamino)pyrazine~2~carbonitrile and pharmaceutically acceptable salts and solvates thereof, that is capable of inhibiting CHK1 and is useful in the treatment of neuroblastomas and/or soft tissue sarcomas.
La présente invention concerne un 5-(5-(2-(3-aminopropoxy)-6-méthoxyphényl)-1H-pyrazol-3-ylamino)pyrazine-2-carbonitrile, ainsi que des sels et solvates pharmaceutiquement acceptables de celui-ci, qui peut inhiber le CHK1 et est utile dans le traitement de neuroblastomes et/ou de sarcomes des tissus mous.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_WO2017015124A1 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | CHK1/2 INHIBITORS FOR USE IN THE TREATMENT OF NEUROBLASTOMAS AND/OR SOFT TISSUE SARCOMAS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T06%3A47%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=STANCATO,%20Louis%20Frank&rft.date=2017-01-26&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO2017015124A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |