MULTIPLE PILL ABUSE-RESISTANT IMMEDIATE RELEASE SOLID DOSAGE FORM OF HYDROCODONE

MULTIPLE PILL ABUSE-RESISTANT IMMEDIATE RELEASE SOLID DOSAGE FORM OF HYDROCODONE

An immediate-release, abuse-resistant solid dosage form comprising melt extrudates of a mixture of: ∙ hydrocodone or its pharmaceutically acceptable salt, ∙ release inhibiting agent comprising one or more reverse enteric polymer and one or more alkalizer and ∙ one or more stabilizers. Forme galéniqu...

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Bibliographische Detailangaben
Hauptverfasser: HANAMANNAVAR, Bramhanand, DHARMADHIKARI, Nitin B, ZALA, Yashoraj R
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:An immediate-release, abuse-resistant solid dosage form comprising melt extrudates of a mixture of: ∙ hydrocodone or its pharmaceutically acceptable salt, ∙ release inhibiting agent comprising one or more reverse enteric polymer and one or more alkalizer and ∙ one or more stabilizers. Forme galénique solide à libération immédiate résistant à la prise abusive comprenant des extrudats fondus d'un mélange : ∙ d'hydrocodone ou de son sel pharmaceutiquement acceptable, ∙ d'un agent d'inhibition de libération comprenant un ou plusieurs polymères entériques inverses et un ou plusieurs agents alcalinisants et ∙ un ou plusieurs agents stabilisants.