MELATONIN ANALOGUES FOR TREATING CANCER

The present invention demonstrates that the compound N-[2-(7-methoxynaphthalen-1-yl) ethyl] acetamide (agomelatine) inhibits the growth of colon cancer cell lines in vitro as well as in vivo, suggesting the oncostatic/cytotoxic role of this compound. The lines having wild-type p53 demonstrated highe...

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Hauptverfasser:	LEÓN LÓPEZ, Josefa, CASADO RUÍZ, Jorge, JIMÉNEZ RUÍZ, Sergio Manuel, SALMERÓN CASTELAR, Javier
Format:	Patent
Sprache:	eng ; fre ; spa
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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