NOVEL HETEROCYCLIC COMPOUNDS AS INHIBITORS OF VANIN-1 ENZYME

Compounds, pharmaceutically acceptable salts thereof, are disclosed wherein the compounds have the structure of Formula (I) as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed. L'invention c...

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Bibliographische Detailangaben
Hauptverfasser: MATHIAS, John Paul, FLICK, Andrew Christopher, STROHBACH, Joseph Walter, GOPALSAMY, Ariamala, CONDON, Jeffrey Scott, CASIMIRO-GARCIA, Agustin, XIANG, Jason Shaoyun, XING, Li Huang, KIRINCICH, Steven J, WANG, Xiaolun
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Compounds, pharmaceutically acceptable salts thereof, are disclosed wherein the compounds have the structure of Formula (I) as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed. L'invention concerne des composés et leurs sels pharmaceutiquement acceptables, les composés présentant la structure représentée par la Formule (I) telle que définie dans la description. L'invention concerne également des compositions pharmaceutiques, des méthodes de traitement, des méthodes de synthèse et des intermédiaires.