CONDENSATION POLYMERS FOR ANTIMICROBIAL APPLICATIONS

The provision of cationic polymers having a cationic repeat unit of formula (I) comprising a positive-charged quarternary ammonium nitrogen as a backbone nitrogen that can be active against Gram -negative, Gram-positive microbes, and/or fungi. The cationic polymers are synthesized by a condensation...

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Hauptverfasser: ENGLER, Amanda C, TEO, Jye Yng, COADY, Daniel J, BREYTA, Gregory, HEDRICK, James L, ONO, Robert J, HAN, Wei, CHAN, Julian M.W, NELSON, Alshakim, LIU, Shaoqiong, ZHANG, Mu San, YANG, Yi Yan, GARCIA, Jeanette M
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creator ENGLER, Amanda C
TEO, Jye Yng
COADY, Daniel J
BREYTA, Gregory
HEDRICK, James L
ONO, Robert J
HAN, Wei
CHAN, Julian M.W
NELSON, Alshakim
LIU, Shaoqiong
ZHANG, Mu San
YANG, Yi Yan
GARCIA, Jeanette M
description The provision of cationic polymers having a cationic repeat unit of formula (I) comprising a positive-charged quarternary ammonium nitrogen as a backbone nitrogen that can be active against Gram -negative, Gram-positive microbes, and/or fungi. The cationic polymers are synthesized by a condensation polymerization in bulk. The initial polymer formed has backbone tertiary nitrogens, which are subsequently quarternized using a suitable quarternizing agent. L'invention concerne des polymères cationiques ayant une unité répétée cationique de formule (I) comprenant un atome d'azote d'ammonium quaternaire à charge positive comme atome d'azote de squelette qui peut être actif contre les bactéries Gram-négatives, Gram-positives et/ou les champignons. Les polymères cationiques sont synthétisés par une polymérisation par condensation en masse. Le polymère initial formé contient des atomes d'azote tertiaire de squelette, qui sont ensuite quaternisés à l'aide d'un agent de quaternisation approprié.
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subjects CHEMISTRY
COMPOSITIONS BASED THEREON
HUMAN NECESSITIES
HYGIENE
MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR PREPARATION OR CHEMICAL WORKING-UP
USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS
title CONDENSATION POLYMERS FOR ANTIMICROBIAL APPLICATIONS
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