ROBUST QUANTIFICATION OF SINGLE MOLECULES IN NEXT-GENERATION SEQUENCING USING NON-RANDOM COMBINATORIAL OLIGONUCLEOTIDE BARCODES

A population of nucleic acid adaptors is provided. In some embodiments, the population contains at least 50,000 different molecular barcode sequences, where the barcode sequences are double-stranded and at least 90% of the barcode sequences have an edit distance of at least 2. In certain cases, the...

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Bibliographische Detailangaben
Hauptverfasser: JI, Hanlee P, LAU, Billy Tsz Cheong
Format: Patent
Sprache:eng ; fre
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