6-AZA-TETRAHYDRO-γ-CARBOLINE DERIVATIVE AND MEDICINAL USE OF SAME
The purpose of the present invention is to provide a composition useful as a therapeutic agent or prophylactic agent which is for stress urinary incontinence and which has agonistic activity on the 5-HT2C receptor. The present invention provides a 6-aza-tetrahydro-γ-carboline derivative represented...
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| creator | GURUBATHAM, Abraham, Rajkumar YOSHIKAWA, Satoru CHAKRABARTI, Anjan VOSS, Matthew, Ernst KIKUCHI, Tsukasa RAI, Sanjay |
| description | The purpose of the present invention is to provide a composition useful as a therapeutic agent or prophylactic agent which is for stress urinary incontinence and which has agonistic activity on the 5-HT2C receptor. The present invention provides a 6-aza-tetrahydro-γ-carboline derivative represented by the chemical formula shown below or a pharmaceutically acceptable acid addition salt thereof.
L'objet de la présente invention est de proposer une composition utile en tant qu'agent thérapeutique ou agent prophylactique utile pour traiter l'incontinence urinaire d'effort et qui a une activité agoniste sur le récepteur 5-HT2C. La présente invention concerne une 6-aza-tétrahydro-gamma-carboline représentée par la formule chimique présentée ci-dessous ou un sel d'addition d'acide pharmaceutiquement acceptable de celle-ci.
本発明は、５－ＨＴ２Ｃ受容体作動活性を有する、腹圧性尿失禁の治療剤又は予防剤として有用な化合物を提供することを目的としている。本発明は、下記の化学式に代表される６－アザ－テトラヒドロ－γ－カルボリン誘導体又はその薬学的に許容される酸付加塩を提供する。 |
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L'objet de la présente invention est de proposer une composition utile en tant qu'agent thérapeutique ou agent prophylactique utile pour traiter l'incontinence urinaire d'effort et qui a une activité agoniste sur le récepteur 5-HT2C. La présente invention concerne une 6-aza-tétrahydro-gamma-carboline représentée par la formule chimique présentée ci-dessous ou un sel d'addition d'acide pharmaceutiquement acceptable de celle-ci.
本発明は、５－ＨＴ２Ｃ受容体作動活性を有する、腹圧性尿失禁の治療剤又は予防剤として有用な化合物を提供することを目的としている。本発明は、下記の化学式に代表される６－アザ－テトラヒドロ－γ－カルボリン誘導体又はその薬学的に許容される酸付加塩を提供する。</description><language>eng ; fre ; jpn</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160929&DB=EPODOC&CC=WO&NR=2016152759A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160929&DB=EPODOC&CC=WO&NR=2016152759A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GURUBATHAM, Abraham, Rajkumar</creatorcontrib><creatorcontrib>YOSHIKAWA, Satoru</creatorcontrib><creatorcontrib>CHAKRABARTI, Anjan</creatorcontrib><creatorcontrib>VOSS, Matthew, Ernst</creatorcontrib><creatorcontrib>KIKUCHI, Tsukasa</creatorcontrib><creatorcontrib>RAI, Sanjay</creatorcontrib><title>6-AZA-TETRAHYDRO-γ-CARBOLINE DERIVATIVE AND MEDICINAL USE OF SAME</title><description>The purpose of the present invention is to provide a composition useful as a therapeutic agent or prophylactic agent which is for stress urinary incontinence and which has agonistic activity on the 5-HT2C receptor. The present invention provides a 6-aza-tetrahydro-γ-carboline derivative represented by the chemical formula shown below or a pharmaceutically acceptable acid addition salt thereof.
L'objet de la présente invention est de proposer une composition utile en tant qu'agent thérapeutique ou agent prophylactique utile pour traiter l'incontinence urinaire d'effort et qui a une activité agoniste sur le récepteur 5-HT2C. La présente invention concerne une 6-aza-tétrahydro-gamma-carboline représentée par la formule chimique présentée ci-dessous ou un sel d'addition d'acide pharmaceutiquement acceptable de celle-ci.
本発明は、５－ＨＴ２Ｃ受容体作動活性を有する、腹圧性尿失禁の治療剤又は予防剤として有用な化合物を提供することを目的としている。本発明は、下記の化学式に代表される６－アザ－テトラヒドロ－γ－カルボリン誘導体又はその薬学的に許容される酸付加塩を提供する。</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHAy03WMctQNcQ0JcvSIdAny1z23WdfZMcjJ38fTz1XBxTXIM8wxxDPMVcHRz0XB19XF09nTz9FHITTYVcHfTSHY0deVh4E1LTGnOJUXSnMzKLu5hjh76KYW5MenFhckJqfmpZbEh_sbGRiaGZoamZtaOhoaE6cKAASnLLU</recordid><startdate>20160929</startdate><enddate>20160929</enddate><creator>GURUBATHAM, Abraham, Rajkumar</creator><creator>YOSHIKAWA, Satoru</creator><creator>CHAKRABARTI, Anjan</creator><creator>VOSS, Matthew, Ernst</creator><creator>KIKUCHI, Tsukasa</creator><creator>RAI, Sanjay</creator><scope>EVB</scope></search><sort><creationdate>20160929</creationdate><title>6-AZA-TETRAHYDRO-γ-CARBOLINE DERIVATIVE AND MEDICINAL USE OF SAME</title><author>GURUBATHAM, Abraham, Rajkumar ; YOSHIKAWA, Satoru ; CHAKRABARTI, Anjan ; VOSS, Matthew, Ernst ; KIKUCHI, Tsukasa ; RAI, Sanjay</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2016152759A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; jpn</language><creationdate>2016</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>GURUBATHAM, Abraham, Rajkumar</creatorcontrib><creatorcontrib>YOSHIKAWA, Satoru</creatorcontrib><creatorcontrib>CHAKRABARTI, Anjan</creatorcontrib><creatorcontrib>VOSS, Matthew, Ernst</creatorcontrib><creatorcontrib>KIKUCHI, Tsukasa</creatorcontrib><creatorcontrib>RAI, Sanjay</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GURUBATHAM, Abraham, Rajkumar</au><au>YOSHIKAWA, Satoru</au><au>CHAKRABARTI, Anjan</au><au>VOSS, Matthew, Ernst</au><au>KIKUCHI, Tsukasa</au><au>RAI, Sanjay</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>6-AZA-TETRAHYDRO-γ-CARBOLINE DERIVATIVE AND MEDICINAL USE OF SAME</title><date>2016-09-29</date><risdate>2016</risdate><abstract>The purpose of the present invention is to provide a composition useful as a therapeutic agent or prophylactic agent which is for stress urinary incontinence and which has agonistic activity on the 5-HT2C receptor. The present invention provides a 6-aza-tetrahydro-γ-carboline derivative represented by the chemical formula shown below or a pharmaceutically acceptable acid addition salt thereof.
L'objet de la présente invention est de proposer une composition utile en tant qu'agent thérapeutique ou agent prophylactique utile pour traiter l'incontinence urinaire d'effort et qui a une activité agoniste sur le récepteur 5-HT2C. La présente invention concerne une 6-aza-tétrahydro-gamma-carboline représentée par la formule chimique présentée ci-dessous ou un sel d'addition d'acide pharmaceutiquement acceptable de celle-ci.
本発明は、５－ＨＴ２Ｃ受容体作動活性を有する、腹圧性尿失禁の治療剤又は予防剤として有用な化合物を提供することを目的としている。本発明は、下記の化学式に代表される６－アザ－テトラヒドロ－γ－カルボリン誘導体又はその薬学的に許容される酸付加塩を提供する。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 6-AZA-TETRAHYDRO-γ-CARBOLINE DERIVATIVE AND MEDICINAL USE OF SAME |
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