STEROL REGULATORY ELEMENT-BINDING PROTEINS (SREBPS) INHIBITORS

This disclosure provides compounds (la) and (lb) and those compounds for use to treat metabolic disorders and hyperproliferative disorders, including administration of the compounds in conjunction with hormone receptor antagonists. La présente invention concerne des composés (la) et (lb) et l'u...

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Hauptverfasser: KALLEM, Satyanarayana, PHAM, Son Minh, JANGIR, Ramniwas, SHINDE, Bharat Uttam, LINDQUIST, Jeffrey, BHATT, Bhawana, GUHA, Mausumee, BHAGWAT, Vikas Ramdas, BERNALES, Sebastian, RAI, Roopa, PUJALA, Brahmam, GUGULOTH, Rambabu
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creator KALLEM, Satyanarayana
PHAM, Son Minh
JANGIR, Ramniwas
SHINDE, Bharat Uttam
LINDQUIST, Jeffrey
BHATT, Bhawana
GUHA, Mausumee
BHAGWAT, Vikas Ramdas
BERNALES, Sebastian
RAI, Roopa
PUJALA, Brahmam
GUGULOTH, Rambabu
description This disclosure provides compounds (la) and (lb) and those compounds for use to treat metabolic disorders and hyperproliferative disorders, including administration of the compounds in conjunction with hormone receptor antagonists. La présente invention concerne des composés (la) et (lb) et l'utilisation de ces composés pour traiter des troubles métaboliques et des désordres hyperprolifératifs, notamment par administration de ces composés conjointement avec des antagonistes des récepteurs hormonaux.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title STEROL REGULATORY ELEMENT-BINDING PROTEINS (SREBPS) INHIBITORS
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