LENTIVIRAL VECTORS FOR EXPRESSION OF MYCOBACTERIUM TUBERCULOSIS ANTIGENS

The invention relates to nucleic acids, including lentiviral vectors and lentiviral vector particles, encoding M. tuberculosis antigens. The invention encompasses these vectors, methods of making the vectors, and methods of using them, including medicinal uses. The vectors can be used for administra...

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Hauptverfasser: SARRY, Emeline, JAMILUDDIN, Mohamad, F, BEJANARIU, Ana
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creator SARRY, Emeline
JAMILUDDIN, Mohamad, F
BEJANARIU, Ana
description The invention relates to nucleic acids, including lentiviral vectors and lentiviral vector particles, encoding M. tuberculosis antigens. The invention encompasses these vectors, methods of making the vectors, and methods of using them, including medicinal uses. The vectors can be used for administration to humans via intramuscular injection to induce immune responses against the M. tuberculosis antigens. L'invention concerne des acides nucléiques, notamment des vecteurs lentiviraux et de particules de vecteurs lentiviraux codant pour des antigènes de M. tuberculosis. L'invention concerne également ces vecteurs, des procédés de préparation desdits vecteurs et leurs procédés d'utilisation, notamment des utilisations médicinales. Les vecteurs de l'invention peuvent être utilisés pour être administrés à des êtres humains par injection intramusculaire dans le but d'induire des réponses immunitaires contre les antigènes de M tuberculosis.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title LENTIVIRAL VECTORS FOR EXPRESSION OF MYCOBACTERIUM TUBERCULOSIS ANTIGENS
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