AN IMPROVED PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF
The present invention refers to novel process for the preparation of Apixaban. Further, the invention also related to a process for the preparation of intermediate of Apixaban from very basic and cheap row material i.e. Aniline which is widely commercially available. The present invention provides p...
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| creator | SURVE, YASHWANT AHIRE, RAMDAS N SATHE, DHANANJAY D DAS, ARIJIT KHANDEKAR, AMIT C |
| description | The present invention refers to novel process for the preparation of Apixaban. Further, the invention also related to a process for the preparation of intermediate of Apixaban from very basic and cheap row material i.e. Aniline which is widely commercially available. The present invention provides process for preparation of Apixaban using a different sequence of synthetic steps and does not involve use of Ullmann reaction.
La présente invention porte sur un nouveau procédé de préparation d'apixaban. En outre, l'invention concerne également un procédé de préparation d'un intermédiaire d'apixaban à partir d'une matière première basique et très bon marché, à savoir de l'aniline qui est largement disponible dans le commerce. La présente invention concerne un procédé de préparation d'apixaban à l'aide d'une séquence différente d'étapes de synthèse et qui n'implique pas l'utilisation d'une réaction d'Ullmann. |
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La présente invention porte sur un nouveau procédé de préparation d'apixaban. En outre, l'invention concerne également un procédé de préparation d'un intermédiaire d'apixaban à partir d'une matière première basique et très bon marché, à savoir de l'aniline qui est largement disponible dans le commerce. La présente invention concerne un procédé de préparation d'apixaban à l'aide d'une séquence différente d'étapes de synthèse et qui n'implique pas l'utilisation d'une réaction d'Ullmann.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2016</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160506&DB=EPODOC&CC=WO&NR=2016035007A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20160506&DB=EPODOC&CC=WO&NR=2016035007A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SURVE, YASHWANT</creatorcontrib><creatorcontrib>AHIRE, RAMDAS N</creatorcontrib><creatorcontrib>SATHE, DHANANJAY D</creatorcontrib><creatorcontrib>DAS, ARIJIT</creatorcontrib><creatorcontrib>KHANDEKAR, AMIT C</creatorcontrib><title>AN IMPROVED PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF</title><description>The present invention refers to novel process for the preparation of Apixaban. Further, the invention also related to a process for the preparation of intermediate of Apixaban from very basic and cheap row material i.e. Aniline which is widely commercially available. The present invention provides process for preparation of Apixaban using a different sequence of synthetic steps and does not involve use of Ullmann reaction.
La présente invention porte sur un nouveau procédé de préparation d'apixaban. En outre, l'invention concerne également un procédé de préparation d'un intermédiaire d'apixaban à partir d'une matière première basique et très bon marché, à savoir de l'aniline qui est largement disponible dans le commerce. La présente invention concerne un procédé de préparation d'apixaban à l'aide d'une séquence différente d'étapes de synthèse et qui n'implique pas l'utilisation d'une réaction d'Ullmann.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2016</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPB19FPw9A0I8g9zdVEAUs6uwcEKbv5BCiEerkC-a4BjkGOIp7-fgr-bgmOAZ4SjE1CDo5-LgqdfiGuQr6uLp2OIazBIdZCrvxsPA2taYk5xKi-U5mZQdnMNcfbQTS3Ij08tLkhMTs1LLYkP9zcyMDQzMDY1MDB3NDYmThUAkTEvAA</recordid><startdate>20160506</startdate><enddate>20160506</enddate><creator>SURVE, YASHWANT</creator><creator>AHIRE, RAMDAS N</creator><creator>SATHE, DHANANJAY D</creator><creator>DAS, ARIJIT</creator><creator>KHANDEKAR, AMIT C</creator><scope>EVB</scope></search><sort><creationdate>20160506</creationdate><title>AN IMPROVED PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF</title><author>SURVE, YASHWANT ; AHIRE, RAMDAS N ; SATHE, DHANANJAY D ; DAS, ARIJIT ; KHANDEKAR, AMIT C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2016035007A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2016</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>SURVE, YASHWANT</creatorcontrib><creatorcontrib>AHIRE, RAMDAS N</creatorcontrib><creatorcontrib>SATHE, DHANANJAY D</creatorcontrib><creatorcontrib>DAS, ARIJIT</creatorcontrib><creatorcontrib>KHANDEKAR, AMIT C</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SURVE, YASHWANT</au><au>AHIRE, RAMDAS N</au><au>SATHE, DHANANJAY D</au><au>DAS, ARIJIT</au><au>KHANDEKAR, AMIT C</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>AN IMPROVED PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF</title><date>2016-05-06</date><risdate>2016</risdate><abstract>The present invention refers to novel process for the preparation of Apixaban. Further, the invention also related to a process for the preparation of intermediate of Apixaban from very basic and cheap row material i.e. Aniline which is widely commercially available. The present invention provides process for preparation of Apixaban using a different sequence of synthetic steps and does not involve use of Ullmann reaction.
La présente invention porte sur un nouveau procédé de préparation d'apixaban. En outre, l'invention concerne également un procédé de préparation d'un intermédiaire d'apixaban à partir d'une matière première basique et très bon marché, à savoir de l'aniline qui est largement disponible dans le commerce. La présente invention concerne un procédé de préparation d'apixaban à l'aide d'une séquence différente d'étapes de synthèse et qui n'implique pas l'utilisation d'une réaction d'Ullmann.</abstract><oa>free_for_read</oa></addata></record> |
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| title | AN IMPROVED PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF |
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