A THERMOSTABLE FREEZE DRIED ROTAVIRUS VACCINE FORMULATION AND PROCESS TO PREPARE THEREOF

The present invention relates to a thermostable freeze dried rotavirus vaccine formulation and the process of preparing the same. More specifically the present invention discloses multivalent thermostable liquid, powder or cake based rotavirus vaccine formulation prepared using the freeze drying pro...

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Hauptverfasser: KALESACHIN, MADAN, MADHU, SHARMA, TARUN, SHUKLA, NIDHI, GILL, DAVINDER, SIKRIWAL, DEEPA, EVANS, ROBERT
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creator KALESACHIN
MADAN, MADHU
SHARMA, TARUN
SHUKLA, NIDHI
GILL, DAVINDER
SIKRIWAL, DEEPA
EVANS, ROBERT
description The present invention relates to a thermostable freeze dried rotavirus vaccine formulation and the process of preparing the same. More specifically the present invention discloses multivalent thermostable liquid, powder or cake based rotavirus vaccine formulation prepared using the freeze drying process, such that the said vaccine formulation possess improved heat-stability, easy to use and transport and highly affordable thereby meeting the requirements of developing and low income country's vaccination program. The said freeze dried rotavirus vaccine formulation along with reconstitution buffer is so engineered to be suitable for filling in appropriate packaging containers/ closures so designed such that they reduce the logistics requirement for storage. La présente invention concerne une formulation de vaccin à rotavirus lyophilisée thermostable et son procédé de préparation. L'invention concerne plus précisément une formulation de vaccin multivalent à rotavirus thermostable à base liquide, de poudre ou de gâteau, préparée en utilisant le processus de lyophilisation, de sorte que ladite formulation de vaccin est plus stable à la chaleur, plus facile à utiliser et à transporter et plus économique, ce qui répond ainsi aux exigences des programmes de vaccination dans les pays en voie de développement et les pays à faible revenu. Ladite formulation de vaccin à rotavirus lyophilisée, et son tampon de reconstitution, sont ainsi produits de manière à être conditionnés dans des récipients/enceintes approprié(e)s pour réduire les exigences logistiques de conservation.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title A THERMOSTABLE FREEZE DRIED ROTAVIRUS VACCINE FORMULATION AND PROCESS TO PREPARE THEREOF
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