HETEROCYCLYL COMPOUNDS AS MEK INHIBITORS

The present disclosure is related to heterocyclyl compounds as MEK inhibitors. These compounds include heterocyclyl compounds of formula (I) and (Ia), their pharmaceutically acceptable salts, their combinations with suitable medicaments, and pharmaceutical compositions thereof. The present disclosur...

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Bibliographische Detailangaben
Hauptverfasser:	DAVE, BHAVESH, PALLE, VENKATA, P, BANERJEE, RAKESH, KUMAR, KAMBOJ, RAJENDER, KUMAR, WETAL, RAJESH, HANGARGE, RAJKUMAR
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure is related to heterocyclyl compounds as MEK inhibitors. These compounds include heterocyclyl compounds of formula (I) and (Ia), their pharmaceutically acceptable salts, their combinations with suitable medicaments, and pharmaceutical compositions thereof. The present disclosure also includes processes of preparation of the compounds and their use in methods of treatment. The compounds as disclosed herein are of Formula (I) below: La présente invention concerne des composés hétérocyclyles utilisés comme inhibiteurs de MEK. Ces composés comprennent des composés hétérocyclyles de formules (I) et (Ia), leurs sels pharmaceutiquement acceptables, leurs associations avec des médicaments appropriés, et des compositions pharmaceutiques correspondantes. La présente invention concerne également des procédés de préparation des composés et leur utilisation dans des méthodes de traitement. Les composés selon la présente invention sont représentés par la formule (I).