METHODS AND SYSTEMS FOR CONVERTING PRECURSOR CELLS INTO GASTRIC TISSUES THROUGH DIRECTED DIFFERENTIATION
Disclosed are methods of inducing formation of a gastric cells and/or a gastric tissue, such as in the form of a gastric organoid. The formation of gastric cells and/or tissue may be carried out by the activating and/or inhibiting of one or more signaling pathways within a precursor cell. Also discl...
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| creator | MCCRACKEN, KYLE, WILLIAM WELLS, JAMES, MACORMACK |
| description | Disclosed are methods of inducing formation of a gastric cells and/or a gastric tissue, such as in the form of a gastric organoid. The formation of gastric cells and/or tissue may be carried out by the activating and/or inhibiting of one or more signaling pathways within a precursor cell. Also disclosed are methods for using the disclosed gastric cells, gastric tissues, and/or gastric organoids derived from precursor cells.
L'invention concerne des procédés d'induction de la formation d'une cellule gastrique et/ou d'un tissu gastrique, par exemple sous la forme d'un organoïde gastrique. La formation de cellules et/ou de tissu gastriques peut être obtenue par l'activation et/ou l'inhibition d'une ou plusieurs voies de signalisation dans une cellule précurseur. L'invention concerne également des procédés d'utilisation des cellules gastriques, des tissus gastriques, et/ou des organoïdes gastriques dérivés des cellules précurseurs. |
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L'invention concerne des procédés d'induction de la formation d'une cellule gastrique et/ou d'un tissu gastrique, par exemple sous la forme d'un organoïde gastrique. La formation de cellules et/ou de tissu gastriques peut être obtenue par l'activation et/ou l'inhibition d'une ou plusieurs voies de signalisation dans une cellule précurseur. L'invention concerne également des procédés d'utilisation des cellules gastriques, des tissus gastriques, et/ou des organoïdes gastriques dérivés des cellules précurseurs.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20151203&DB=EPODOC&CC=WO&NR=2015183920A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20151203&DB=EPODOC&CC=WO&NR=2015183920A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MCCRACKEN, KYLE, WILLIAM</creatorcontrib><creatorcontrib>WELLS, JAMES, MACORMACK</creatorcontrib><title>METHODS AND SYSTEMS FOR CONVERTING PRECURSOR CELLS INTO GASTRIC TISSUES THROUGH DIRECTED DIFFERENTIATION</title><description>Disclosed are methods of inducing formation of a gastric cells and/or a gastric tissue, such as in the form of a gastric organoid. The formation of gastric cells and/or tissue may be carried out by the activating and/or inhibiting of one or more signaling pathways within a precursor cell. Also disclosed are methods for using the disclosed gastric cells, gastric tissues, and/or gastric organoids derived from precursor cells.
L'invention concerne des procédés d'induction de la formation d'une cellule gastrique et/ou d'un tissu gastrique, par exemple sous la forme d'un organoïde gastrique. La formation de cellules et/ou de tissu gastriques peut être obtenue par l'activation et/ou l'inhibition d'une ou plusieurs voies de signalisation dans une cellule précurseur. L'invention concerne également des procédés d'utilisation des cellules gastriques, des tissus gastriques, et/ou des organoïdes gastriques dérivés des cellules précurseurs.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNissKwjAQAHvxIOo_LHgW-kDQY0g2zUJNJLtVPJUiEQ-ihfr_WMEP8DTDMPPsfkBxwTAob4AvLHhgsCGCDv6EUcjXcIyo28jfiE3DQF4C1IolkgYh5hYZxMXQ1g4MTbegmcRajOiFlFDwy2x26x9jWv24yNYWRbtNGl5dGof-mp7p3Z1DmRfbYlfty1yV1X_XB1P9NzM</recordid><startdate>20151203</startdate><enddate>20151203</enddate><creator>MCCRACKEN, KYLE, WILLIAM</creator><creator>WELLS, JAMES, MACORMACK</creator><scope>EVB</scope></search><sort><creationdate>20151203</creationdate><title>METHODS AND SYSTEMS FOR CONVERTING PRECURSOR CELLS INTO GASTRIC TISSUES THROUGH DIRECTED DIFFERENTIATION</title><author>MCCRACKEN, KYLE, WILLIAM ; WELLS, JAMES, MACORMACK</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2015183920A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2015</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>MCCRACKEN, KYLE, WILLIAM</creatorcontrib><creatorcontrib>WELLS, JAMES, MACORMACK</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MCCRACKEN, KYLE, WILLIAM</au><au>WELLS, JAMES, MACORMACK</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHODS AND SYSTEMS FOR CONVERTING PRECURSOR CELLS INTO GASTRIC TISSUES THROUGH DIRECTED DIFFERENTIATION</title><date>2015-12-03</date><risdate>2015</risdate><abstract>Disclosed are methods of inducing formation of a gastric cells and/or a gastric tissue, such as in the form of a gastric organoid. The formation of gastric cells and/or tissue may be carried out by the activating and/or inhibiting of one or more signaling pathways within a precursor cell. Also disclosed are methods for using the disclosed gastric cells, gastric tissues, and/or gastric organoids derived from precursor cells.
L'invention concerne des procédés d'induction de la formation d'une cellule gastrique et/ou d'un tissu gastrique, par exemple sous la forme d'un organoïde gastrique. La formation de cellules et/ou de tissu gastriques peut être obtenue par l'activation et/ou l'inhibition d'une ou plusieurs voies de signalisation dans une cellule précurseur. L'invention concerne également des procédés d'utilisation des cellules gastriques, des tissus gastriques, et/ou des organoïdes gastriques dérivés des cellules précurseurs.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | METHODS AND SYSTEMS FOR CONVERTING PRECURSOR CELLS INTO GASTRIC TISSUES THROUGH DIRECTED DIFFERENTIATION |
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