THERAPEUTIC COMPOUNDS AND USES THEREOF

The present invention relates to compounds useful as inhibitors of one or more histone demethylses, such as KDM5. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various diso...

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Bibliographische Detailangaben
Hauptverfasser: GEHLING, VICTOR S, ORTWINE, DAN, ZHANG, BIRONG, ALBRECHT, BRIAN K, DRAGOVICH, PETER, LIANG, JUN, HARMANGE, JEANRISTOPHE, LAI, TOMMY, LABADIE, SHARADA, KIEFER, JIM
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention relates to compounds useful as inhibitors of one or more histone demethylses, such as KDM5. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders. La présente invention concerne des composés utiles en tant qu'inhibiteurs d'une ou de plusieurs histones déméthylases, tel que KDM5. L'invention concerne également des compositions pharmaceutiquement acceptables comprenant les composés de la présente invention, ainsi que des méthodes d'utilisation desdites compositions dans le traitement de divers troubles.