NOVEL ANTIBODY SPECIFIC FOR TSPAN8 AND USES THEREOF

The present invention relates to a novel antibody specifically binding to the TSPAN8 (tetraspanin 8) and uses thereof. More particularly, the present invention relates to an antibody specifically binding to the LEL (large extracellular loop) of TSPAN8, a method for preparing the antibody, a composit...

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Bibliographische Detailangaben
Hauptverfasser:	PARK, CHANG SIK, GO, NAM KYUNG, KIM, TAEK-KEUN, KI, MIN KYOUNG, LEE, WOO RAN, LEE, SUKMOOK, JEOUNG, MEE HYUN, CHOI, JONG RIP
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a novel antibody specifically binding to the TSPAN8 (tetraspanin 8) and uses thereof. More particularly, the present invention relates to an antibody specifically binding to the LEL (large extracellular loop) of TSPAN8, a method for preparing the antibody, a composition for the suppression of cancer and/or cancer metastasis comprising the antibody, a method for suppressing cancer and/or cancer metastasis by administering the antibody or the composition, a composition for preventing or treating cancer and/or cancer metastasis comprising the antibody, a method for preventing or treating cancer and/or cancer metastasis by administering the antibody or the composition, a composition for diagnosing cancer and/or cancer metastasis comprising the antibody, a kit for diagnosing cancer comprising the composition, a method for diagnosing cancer using the composition, a composition for the suppression of cancer and/or cancer metastasis comprising a material for inhibiting expression of TSPAN8, a kit for cancer and/or cancer metastasis comprising the composition, a method for suppressing cancer and/or cancer metastasis or treating cancer using the composition, and the use of the LEL of TSPAN8 as an epitope for an antibody suppressive of cancer and/or cancer metastasis. La présente invention concerne un nouvel anticorps se liant spécifiquement à la TSPAN8 (tétraspanine 8) et ses utilisations. Plus particulièrement, la présente invention concerne un anticorps se liant particulièrement à la LEL (grande boucle extracellulaire) de la TSPAN8, un procédé de préparation de l'anticorps, une composition de suppression du cancer et/ou des métastases cancéreuses comprenant l'anticorps, un procédé de suppression du cancer et/ou des métastases cancéreuses par l'administration de l'anticorps ou de la composition, une composition de prévention ou de traitement du cancer et/ou des métastases cancéreuses comprenant l'anticorps, un procédé de prévention ou de traitement du cancer et/ou des métastases cancéreuses par l'administration de l'anticorps ou de la composition, une composition de diagnostic du cancer et/ou des métastases cancéreuses comprenant l'anticorps, une trousse de diagnostic du cancer comprenant la composition, un procédé de diagnostic du cancer utilisant la composition, une composition pour la suppression du cancer et/ou des métastases du cancer comprenant un matériau pour inhiber l'expression de TSPAN8, une trousse pour le cancer et/ou l