NANOSTRUCTURED COMPOSITION COMPRISING INDOMETHACINE, ITS PHARMACEUTICALLY ACCEPTABLE SALTS AND CO-CRYSTALS AND PROCESS FOR THE PREPARATION THEREOF
The invention relates to a nanostructured (nanoparticular) composition comprising Indomethacine, its pharmaceutically acceptable salts and co-crystals, processes for the preparation thereof, and compositions useful for pharmaceutical applications. The size of the nanoparticles according to the inven...
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| creator | ÖTVÖS, ZSOLT HELTOVICS, GÁBOR FILIPCSEI, GENOVÉVA DARVAS, FERENC |
| description | The invention relates to a nanostructured (nanoparticular) composition comprising Indomethacine, its pharmaceutically acceptable salts and co-crystals, processes for the preparation thereof, and compositions useful for pharmaceutical applications. The size of the nanoparticles according to the invention is smaller than 500 nm. Indomethacine (INN) or Indomethacine (USAN, previously BAN) is a non-steroidal anti-inflammatory drug (NSAID), which is used for the treatment of fever, inflammation, spasm, swells and inflammations. The machanism of action of Indomethacine is the inhibition of the synthesis of prostaglandin. It is marketed under the trade names of Indocin, Indocid, Indochron E-R, and Indocin-SR.
La présente invention concerne une composition nanostructurée (nanoparticulaire) comprenant de l'indométacine, ses sels pharmaceutiquement acceptables et ses co-cristaux, ainsi que ses procédés de préparation, et des compositions utiles pour des applications pharmaceutiques. La taille des nanoparticules selon la présente invention est inférieure à 500 nm. L'indométacine (INN) ou l'indométacine (USAN, précédemment BAN) est un médicament anti-inflammatoire non stéroïdien (AINS) utilisé dans le traitement de la fièvre, des inflammations, des spasmes, des gonflements et des inflammations. Le mécanisme d'action de l'indométacine est l'inhibition de la synthèse de la prostaglandine. L'indométacine est commercialisée sous les dénominations commerciales Indocin, Indocid, Indochron, E-R, et Indocin-SR. |
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La présente invention concerne une composition nanostructurée (nanoparticulaire) comprenant de l'indométacine, ses sels pharmaceutiquement acceptables et ses co-cristaux, ainsi que ses procédés de préparation, et des compositions utiles pour des applications pharmaceutiques. La taille des nanoparticules selon la présente invention est inférieure à 500 nm. L'indométacine (INN) ou l'indométacine (USAN, précédemment BAN) est un médicament anti-inflammatoire non stéroïdien (AINS) utilisé dans le traitement de la fièvre, des inflammations, des spasmes, des gonflements et des inflammations. Le mécanisme d'action de l'indométacine est l'inhibition de la synthèse de la prostaglandine. L'indométacine est commercialisée sous les dénominations commerciales Indocin, Indocid, Indochron, E-R, et Indocin-SR.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150903&DB=EPODOC&CC=WO&NR=2015128685A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150903&DB=EPODOC&CC=WO&NR=2015128685A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ÖTVÖS, ZSOLT</creatorcontrib><creatorcontrib>HELTOVICS, GÁBOR</creatorcontrib><creatorcontrib>FILIPCSEI, GENOVÉVA</creatorcontrib><creatorcontrib>DARVAS, FERENC</creatorcontrib><title>NANOSTRUCTURED COMPOSITION COMPRISING INDOMETHACINE, ITS PHARMACEUTICALLY ACCEPTABLE SALTS AND CO-CRYSTALS AND PROCESS FOR THE PREPARATION THEREOF</title><description>The invention relates to a nanostructured (nanoparticular) composition comprising Indomethacine, its pharmaceutically acceptable salts and co-crystals, processes for the preparation thereof, and compositions useful for pharmaceutical applications. The size of the nanoparticles according to the invention is smaller than 500 nm. Indomethacine (INN) or Indomethacine (USAN, previously BAN) is a non-steroidal anti-inflammatory drug (NSAID), which is used for the treatment of fever, inflammation, spasm, swells and inflammations. The machanism of action of Indomethacine is the inhibition of the synthesis of prostaglandin. It is marketed under the trade names of Indocin, Indocid, Indochron E-R, and Indocin-SR.
La présente invention concerne une composition nanostructurée (nanoparticulaire) comprenant de l'indométacine, ses sels pharmaceutiquement acceptables et ses co-cristaux, ainsi que ses procédés de préparation, et des compositions utiles pour des applications pharmaceutiques. La taille des nanoparticules selon la présente invention est inférieure à 500 nm. L'indométacine (INN) ou l'indométacine (USAN, précédemment BAN) est un médicament anti-inflammatoire non stéroïdien (AINS) utilisé dans le traitement de la fièvre, des inflammations, des spasmes, des gonflements et des inflammations. Le mécanisme d'action de l'indométacine est l'inhibition de la synthèse de la prostaglandine. L'indométacine est commercialisée sous les dénominations commerciales Indocin, Indocid, Indochron, E-R, et Indocin-SR.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjUsKwkAQRLNxIeodBtwqGEVx27YdMzCZHno6iKsQZFyJCnoST2z8HMBV1YNHVT97evAcVWrUWmhrkKvA0apl_-lio_U7Y_2WK9IS0HqaGKvRhBKkAqRaLYJzBwOIFBQ2jkwE1xng33tTlENUcF8OwkgxmoLFaEkdUwCBz1_HQlwMs96pPd_T6JeDbFyQYjlNt2uT7rf2mC7p0ex5PsuX-Xy9Wi8hX_xnvQBrXUK_</recordid><startdate>20150903</startdate><enddate>20150903</enddate><creator>ÖTVÖS, ZSOLT</creator><creator>HELTOVICS, GÁBOR</creator><creator>FILIPCSEI, GENOVÉVA</creator><creator>DARVAS, FERENC</creator><scope>EVB</scope></search><sort><creationdate>20150903</creationdate><title>NANOSTRUCTURED COMPOSITION COMPRISING INDOMETHACINE, ITS PHARMACEUTICALLY ACCEPTABLE SALTS AND CO-CRYSTALS AND PROCESS FOR THE PREPARATION THEREOF</title><author>ÖTVÖS, ZSOLT ; HELTOVICS, GÁBOR ; FILIPCSEI, GENOVÉVA ; DARVAS, FERENC</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2015128685A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2015</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>ÖTVÖS, ZSOLT</creatorcontrib><creatorcontrib>HELTOVICS, GÁBOR</creatorcontrib><creatorcontrib>FILIPCSEI, GENOVÉVA</creatorcontrib><creatorcontrib>DARVAS, FERENC</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ÖTVÖS, ZSOLT</au><au>HELTOVICS, GÁBOR</au><au>FILIPCSEI, GENOVÉVA</au><au>DARVAS, FERENC</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NANOSTRUCTURED COMPOSITION COMPRISING INDOMETHACINE, ITS PHARMACEUTICALLY ACCEPTABLE SALTS AND CO-CRYSTALS AND PROCESS FOR THE PREPARATION THEREOF</title><date>2015-09-03</date><risdate>2015</risdate><abstract>The invention relates to a nanostructured (nanoparticular) composition comprising Indomethacine, its pharmaceutically acceptable salts and co-crystals, processes for the preparation thereof, and compositions useful for pharmaceutical applications. The size of the nanoparticles according to the invention is smaller than 500 nm. Indomethacine (INN) or Indomethacine (USAN, previously BAN) is a non-steroidal anti-inflammatory drug (NSAID), which is used for the treatment of fever, inflammation, spasm, swells and inflammations. The machanism of action of Indomethacine is the inhibition of the synthesis of prostaglandin. It is marketed under the trade names of Indocin, Indocid, Indochron E-R, and Indocin-SR.
La présente invention concerne une composition nanostructurée (nanoparticulaire) comprenant de l'indométacine, ses sels pharmaceutiquement acceptables et ses co-cristaux, ainsi que ses procédés de préparation, et des compositions utiles pour des applications pharmaceutiques. La taille des nanoparticules selon la présente invention est inférieure à 500 nm. L'indométacine (INN) ou l'indométacine (USAN, précédemment BAN) est un médicament anti-inflammatoire non stéroïdien (AINS) utilisé dans le traitement de la fièvre, des inflammations, des spasmes, des gonflements et des inflammations. Le mécanisme d'action de l'indométacine est l'inhibition de la synthèse de la prostaglandine. L'indométacine est commercialisée sous les dénominations commerciales Indocin, Indocid, Indochron, E-R, et Indocin-SR.</abstract><oa>free_for_read</oa></addata></record> |
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| title | NANOSTRUCTURED COMPOSITION COMPRISING INDOMETHACINE, ITS PHARMACEUTICALLY ACCEPTABLE SALTS AND CO-CRYSTALS AND PROCESS FOR THE PREPARATION THEREOF |
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