CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS
Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa- 8-azaspiro[4.5] decane. Also disclo...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | WELLS, JAMES A RENSLO, ADAM R LAUTERWASSER, ERICA M.W FONTAINE, SHAUN D SPANGLER, BENJAMIN B |
| description | Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa- 8-azaspiro[4.5] decane. Also disclosed is a pharmaceutical composition containing the compound and a phannaceutically acceptable carrier.
L'invention concerne, inter alia, des compositions de promédicaments et des procédés d'utilisation de celles-ci pour le traitement et la détection d'une maladie. Plus spécifiquement, l'invention porte sur un composé de formule (I) comportant des cycles pipéridine et 1,2,4-trioxolane spiro-fusionnés, à savoir du 1,2,4-trioxa- 8-azaspiro[4.5] décane. L'invention concerne également une composition pharmaceutique contenant le composé et un support pharmaceutiquement acceptable. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO2015123595A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO2015123595A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO2015123595A13</originalsourceid><addsrcrecordid>eNrjZLB1jnT28XRWCHAN8o_wdHENVnAMVggI8ncJCnUPVnDzD1IIdvVxdQ7xDHNVcHH1AVJBkQr-bgqO7q5-IcE8DKxpiTnFqbxQmptB2c01xNlDN7UgPz61uCAxOTUvtSQ-3N_IwNDU0MjY1NLU0dCYOFUA3NIq0A</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS</title><source>esp@cenet</source><creator>WELLS, JAMES A ; RENSLO, ADAM R ; LAUTERWASSER, ERICA M.W ; FONTAINE, SHAUN D ; SPANGLER, BENJAMIN B</creator><creatorcontrib>WELLS, JAMES A ; RENSLO, ADAM R ; LAUTERWASSER, ERICA M.W ; FONTAINE, SHAUN D ; SPANGLER, BENJAMIN B</creatorcontrib><description>Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa- 8-azaspiro[4.5] decane. Also disclosed is a pharmaceutical composition containing the compound and a phannaceutically acceptable carrier.
L'invention concerne, inter alia, des compositions de promédicaments et des procédés d'utilisation de celles-ci pour le traitement et la détection d'une maladie. Plus spécifiquement, l'invention porte sur un composé de formule (I) comportant des cycles pipéridine et 1,2,4-trioxolane spiro-fusionnés, à savoir du 1,2,4-trioxa- 8-azaspiro[4.5] décane. L'invention concerne également une composition pharmaceutique contenant le composé et un support pharmaceutiquement acceptable.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150820&DB=EPODOC&CC=WO&NR=2015123595A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150820&DB=EPODOC&CC=WO&NR=2015123595A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WELLS, JAMES A</creatorcontrib><creatorcontrib>RENSLO, ADAM R</creatorcontrib><creatorcontrib>LAUTERWASSER, ERICA M.W</creatorcontrib><creatorcontrib>FONTAINE, SHAUN D</creatorcontrib><creatorcontrib>SPANGLER, BENJAMIN B</creatorcontrib><title>CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS</title><description>Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa- 8-azaspiro[4.5] decane. Also disclosed is a pharmaceutical composition containing the compound and a phannaceutically acceptable carrier.
L'invention concerne, inter alia, des compositions de promédicaments et des procédés d'utilisation de celles-ci pour le traitement et la détection d'une maladie. Plus spécifiquement, l'invention porte sur un composé de formule (I) comportant des cycles pipéridine et 1,2,4-trioxolane spiro-fusionnés, à savoir du 1,2,4-trioxa- 8-azaspiro[4.5] décane. L'invention concerne également une composition pharmaceutique contenant le composé et un support pharmaceutiquement acceptable.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLB1jnT28XRWCHAN8o_wdHENVnAMVggI8ncJCnUPVnDzD1IIdvVxdQ7xDHNVcHH1AVJBkQr-bgqO7q5-IcE8DKxpiTnFqbxQmptB2c01xNlDN7UgPz61uCAxOTUvtSQ-3N_IwNDU0MjY1NLU0dCYOFUA3NIq0A</recordid><startdate>20150820</startdate><enddate>20150820</enddate><creator>WELLS, JAMES A</creator><creator>RENSLO, ADAM R</creator><creator>LAUTERWASSER, ERICA M.W</creator><creator>FONTAINE, SHAUN D</creator><creator>SPANGLER, BENJAMIN B</creator><scope>EVB</scope></search><sort><creationdate>20150820</creationdate><title>CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS</title><author>WELLS, JAMES A ; RENSLO, ADAM R ; LAUTERWASSER, ERICA M.W ; FONTAINE, SHAUN D ; SPANGLER, BENJAMIN B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2015123595A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2015</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>WELLS, JAMES A</creatorcontrib><creatorcontrib>RENSLO, ADAM R</creatorcontrib><creatorcontrib>LAUTERWASSER, ERICA M.W</creatorcontrib><creatorcontrib>FONTAINE, SHAUN D</creatorcontrib><creatorcontrib>SPANGLER, BENJAMIN B</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WELLS, JAMES A</au><au>RENSLO, ADAM R</au><au>LAUTERWASSER, ERICA M.W</au><au>FONTAINE, SHAUN D</au><au>SPANGLER, BENJAMIN B</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS</title><date>2015-08-20</date><risdate>2015</risdate><abstract>Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa- 8-azaspiro[4.5] decane. Also disclosed is a pharmaceutical composition containing the compound and a phannaceutically acceptable carrier.
L'invention concerne, inter alia, des compositions de promédicaments et des procédés d'utilisation de celles-ci pour le traitement et la détection d'une maladie. Plus spécifiquement, l'invention porte sur un composé de formule (I) comportant des cycles pipéridine et 1,2,4-trioxolane spiro-fusionnés, à savoir du 1,2,4-trioxa- 8-azaspiro[4.5] décane. L'invention concerne également une composition pharmaceutique contenant le composé et un support pharmaceutiquement acceptable.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_WO2015123595A1 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T02%3A26%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=WELLS,%20JAMES%20A&rft.date=2015-08-20&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO2015123595A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |