POLYNUCLEOTIDE, POLYPEPTIDE WITH IMMUNOSUPPRESIVE ACTIVITY, EXPRESSION CASSETTE, EXPRESSION VECTOR, HOST CELL, PHARMACEUTICAL COMPOSITION, METHODS FOR PRODUCING A POLYPETIDE WITH IMMUNOSUPPRESIVE ACTIVITY AND FOR PREVENTING OR TREATING CONDITIONS THAT REQUIRE IMMUNOSUPPRESION AND USE OF A POLYPEPTIDE

POLYNUCLEOTIDE, POLYPEPTIDE WITH IMMUNOSUPPRESIVE ACTIVITY, EXPRESSION CASSETTE, EXPRESSION VECTOR, HOST CELL, PHARMACEUTICAL COMPOSITION, METHODS FOR PRODUCING A POLYPETIDE WITH IMMUNOSUPPRESIVE ACTIVITY AND FOR PREVENTING OR TREATING CONDITIONS THAT REQUIRE IMMUNOSUPPRESION AND USE OF A POLYPEPTIDE

This invention refers to polynucleotides and non-hemorrhagic and non-immunogenic polypeptides of selective immunosuppressive activity on production of antibodies to antigens of different natures. The polypeptides described herein are useful for preparing pharmaceutical compositions for prevention or...

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Bibliographische Detailangaben
Hauptverfasser: MAGNOLI, FÁBIO, CARLOS, QUEIROZ, GISELLE, PIDDE, TAMBOURGI, DENISE, V, SANT'ANNA, OSVALDO, AUGUSTO, BRAZIL, ESTEVES, PACHECO, OGARI, DE CASTRO
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:This invention refers to polynucleotides and non-hemorrhagic and non-immunogenic polypeptides of selective immunosuppressive activity on production of antibodies to antigens of different natures. The polypeptides described herein are useful for preparing pharmaceutical compositions for prevention or treatment of conditions that require immunosuppression, preferably, inflammatory, autoimmune, allergic and infectious diseases and rejection to transplanted organs. Cette invention concerne des polynucléotides et des polypeptides non hémorragiques et non immunogènes ayant une activité immunosuppressive sélective sur la production d'anticorps dirigés contre des antigènes de natures différentes. Les polypeptides ci-décrits sont utiles pour préparer des compositions pharmaceutiques destinées à prévenir ou à traiter des affections qui exigent l'immunosuppression, de préférence, les maladies inflammatoires, auto-immunes, allergiques et infectieuses et le rejet des greffes d'organes.