NOVEL 20(S)-SULFONYLAMIDINE DERIVATIVES OF CAMPTOTHECIN AND THE USE THEREOF AS A POTENT ANTITUMOR AGENT
The present invention is related to novel 20-sulfonylamidine derivatives of camptothecin (1), method of synthesizing the same, and use thereof as an antitumor agent, for examples an antitumor agent for treating nasopharyngeal, lung, breast or prostate cancer. La présente invention concerne de nouvea...
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| creator | LEE, KUO-HSIUNG SHYU, WOEIRNG WANG, MEI-JUAN LIN, CHEN-HUAN ZHANG, ZHI-JUN WANG, CHIH-YA GOTO, MASUO ZHAO, YONG-LONG TENG, CHE-MING CHANG, LINGU QIAN, KEDUO HUNG, HSIN-YI YANG, XIAOMING LIU, YING-QIAN WU, TIAN-SHUNG HSIEH, MIN-TSANG WU, YANGANG YANG, LIU PAN, SHIOW-LIN KUO, SHENGU HSU, CHUNG Y |
| description | The present invention is related to novel 20-sulfonylamidine derivatives of camptothecin (1), method of synthesizing the same, and use thereof as an antitumor agent, for examples an antitumor agent for treating nasopharyngeal, lung, breast or prostate cancer.
La présente invention concerne de nouveaux dérivés 20-sulfonylamidine de camptothécine (1), leur procédé de synthèse, et leur utilisation en tant qu'agent antitumoral, par exemple pour le traitement de cancers du rhinopharynx, du sein, du poumon ou de la prostate. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | NOVEL 20(S)-SULFONYLAMIDINE DERIVATIVES OF CAMPTOTHECIN AND THE USE THEREOF AS A POTENT ANTITUMOR AGENT |
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