GLUTAMATE RECEPTOR PHOTOMODULATORS
The present invention relates to the discovery of particular aromatic compounds of formula (1), possessing activity as modulators of metabotropic glutamate receptors (mGluR) whose modulatory activity on the receptor may be controlled by irradiation with suitable light resulting in the optical contro...
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| creator | ROVIRA ALGANS, XAVIER GÓMEZ SANTACANA, XAVIER GOROSTIZA LANGA, PAU GIRALDO ARJONILLA, JESÚS GOUDET, CYRIL PIN, JEAN PHILIPPE LLEBARIA SOLDEVILA, AMADEO PITTOLO, SILVIA |
| description | The present invention relates to the discovery of particular aromatic compounds of formula (1), possessing activity as modulators of metabotropic glutamate receptors (mGluR) whose modulatory activity on the receptor may be controlled by irradiation with suitable light resulting in the optical control of receptor biological function, to the use of said compounds as a medicament, and to pharmaceutical compositions comprising said compounds of formula (1).
La présente invention se rapporte à la découverte de composés aromatiques particuliers de formule (1), possédant une activité en tant que modulateurs des récepteurs métabotropiques du glutamate (mGluR) dont l'activité modulatrice sur le récepteur peut être commandée par irradiation avec une lumière appropriée, ce qui provoque la commande optique de la fonction biologique du récepteur; l'invention se rapporte également à l'utilisation desdits composés comme médicament, et à des compositions pharmaceutiques comprenant lesdits composés de formule (1). |
| format | Patent |
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La présente invention se rapporte à la découverte de composés aromatiques particuliers de formule (1), possédant une activité en tant que modulateurs des récepteurs métabotropiques du glutamate (mGluR) dont l'activité modulatrice sur le récepteur peut être commandée par irradiation avec une lumière appropriée, ce qui provoque la commande optique de la fonction biologique du récepteur; l'invention se rapporte également à l'utilisation desdits composés comme médicament, et à des compositions pharmaceutiques comprenant lesdits composés de formule (1).</description><language>eng ; fre</language><subject>ADHESIVES ; CHEMISTRY ; DYES ; HETEROCYCLIC COMPOUNDS ; LAKES ; METALLURGY ; MISCELLANEOUS APPLICATIONS OF MATERIALS ; MISCELLANEOUS COMPOSITIONS ; MORDANTS ; NATURAL RESINS ; ORGANIC CHEMISTRY ; ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES ; PAINTS ; POLISHES</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150402&DB=EPODOC&CC=WO&NR=2015044358A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25566,76549</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150402&DB=EPODOC&CC=WO&NR=2015044358A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ROVIRA ALGANS, XAVIER</creatorcontrib><creatorcontrib>GÓMEZ SANTACANA, XAVIER</creatorcontrib><creatorcontrib>GOROSTIZA LANGA, PAU</creatorcontrib><creatorcontrib>GIRALDO ARJONILLA, JESÚS</creatorcontrib><creatorcontrib>GOUDET, CYRIL</creatorcontrib><creatorcontrib>PIN, JEAN PHILIPPE</creatorcontrib><creatorcontrib>LLEBARIA SOLDEVILA, AMADEO</creatorcontrib><creatorcontrib>PITTOLO, SILVIA</creatorcontrib><title>GLUTAMATE RECEPTOR PHOTOMODULATORS</title><description>The present invention relates to the discovery of particular aromatic compounds of formula (1), possessing activity as modulators of metabotropic glutamate receptors (mGluR) whose modulatory activity on the receptor may be controlled by irradiation with suitable light resulting in the optical control of receptor biological function, to the use of said compounds as a medicament, and to pharmaceutical compositions comprising said compounds of formula (1).
La présente invention se rapporte à la découverte de composés aromatiques particuliers de formule (1), possédant une activité en tant que modulateurs des récepteurs métabotropiques du glutamate (mGluR) dont l'activité modulatrice sur le récepteur peut être commandée par irradiation avec une lumière appropriée, ce qui provoque la commande optique de la fonction biologique du récepteur; l'invention se rapporte également à l'utilisation desdits composés comme médicament, et à des compositions pharmaceutiques comprenant lesdits composés de formule (1).</description><subject>ADHESIVES</subject><subject>CHEMISTRY</subject><subject>DYES</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>LAKES</subject><subject>METALLURGY</subject><subject>MISCELLANEOUS APPLICATIONS OF MATERIALS</subject><subject>MISCELLANEOUS COMPOSITIONS</subject><subject>MORDANTS</subject><subject>NATURAL RESINS</subject><subject>ORGANIC CHEMISTRY</subject><subject>ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES</subject><subject>PAINTS</subject><subject>POLISHES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFBy9wkNcfR1DHFVCHJ1dg0I8Q9SCPDwD_H39XcJ9XEEcoN5GFjTEnOKU3mhNDeDsptriLOHbmpBfnxqcUFicmpeakl8uL-RgaGpgYmJsamFo5ExcaoA8lwj1w</recordid><startdate>20150402</startdate><enddate>20150402</enddate><creator>ROVIRA ALGANS, XAVIER</creator><creator>GÓMEZ SANTACANA, XAVIER</creator><creator>GOROSTIZA LANGA, PAU</creator><creator>GIRALDO ARJONILLA, JESÚS</creator><creator>GOUDET, CYRIL</creator><creator>PIN, JEAN PHILIPPE</creator><creator>LLEBARIA SOLDEVILA, AMADEO</creator><creator>PITTOLO, SILVIA</creator><scope>EVB</scope></search><sort><creationdate>20150402</creationdate><title>GLUTAMATE RECEPTOR PHOTOMODULATORS</title><author>ROVIRA ALGANS, XAVIER ; GÓMEZ SANTACANA, XAVIER ; GOROSTIZA LANGA, PAU ; GIRALDO ARJONILLA, JESÚS ; GOUDET, CYRIL ; PIN, JEAN PHILIPPE ; LLEBARIA SOLDEVILA, AMADEO ; PITTOLO, SILVIA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2015044358A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2015</creationdate><topic>ADHESIVES</topic><topic>CHEMISTRY</topic><topic>DYES</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>LAKES</topic><topic>METALLURGY</topic><topic>MISCELLANEOUS APPLICATIONS OF MATERIALS</topic><topic>MISCELLANEOUS COMPOSITIONS</topic><topic>MORDANTS</topic><topic>NATURAL RESINS</topic><topic>ORGANIC CHEMISTRY</topic><topic>ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES</topic><topic>PAINTS</topic><topic>POLISHES</topic><toplevel>online_resources</toplevel><creatorcontrib>ROVIRA ALGANS, XAVIER</creatorcontrib><creatorcontrib>GÓMEZ SANTACANA, XAVIER</creatorcontrib><creatorcontrib>GOROSTIZA LANGA, PAU</creatorcontrib><creatorcontrib>GIRALDO ARJONILLA, JESÚS</creatorcontrib><creatorcontrib>GOUDET, CYRIL</creatorcontrib><creatorcontrib>PIN, JEAN PHILIPPE</creatorcontrib><creatorcontrib>LLEBARIA SOLDEVILA, AMADEO</creatorcontrib><creatorcontrib>PITTOLO, SILVIA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ROVIRA ALGANS, XAVIER</au><au>GÓMEZ SANTACANA, XAVIER</au><au>GOROSTIZA LANGA, PAU</au><au>GIRALDO ARJONILLA, JESÚS</au><au>GOUDET, CYRIL</au><au>PIN, JEAN PHILIPPE</au><au>LLEBARIA SOLDEVILA, AMADEO</au><au>PITTOLO, SILVIA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>GLUTAMATE RECEPTOR PHOTOMODULATORS</title><date>2015-04-02</date><risdate>2015</risdate><abstract>The present invention relates to the discovery of particular aromatic compounds of formula (1), possessing activity as modulators of metabotropic glutamate receptors (mGluR) whose modulatory activity on the receptor may be controlled by irradiation with suitable light resulting in the optical control of receptor biological function, to the use of said compounds as a medicament, and to pharmaceutical compositions comprising said compounds of formula (1).
La présente invention se rapporte à la découverte de composés aromatiques particuliers de formule (1), possédant une activité en tant que modulateurs des récepteurs métabotropiques du glutamate (mGluR) dont l'activité modulatrice sur le récepteur peut être commandée par irradiation avec une lumière appropriée, ce qui provoque la commande optique de la fonction biologique du récepteur; l'invention se rapporte également à l'utilisation desdits composés comme médicament, et à des compositions pharmaceutiques comprenant lesdits composés de formule (1).</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ADHESIVES CHEMISTRY DYES HETEROCYCLIC COMPOUNDS LAKES METALLURGY MISCELLANEOUS APPLICATIONS OF MATERIALS MISCELLANEOUS COMPOSITIONS MORDANTS NATURAL RESINS ORGANIC CHEMISTRY ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES PAINTS POLISHES |
| title | GLUTAMATE RECEPTOR PHOTOMODULATORS |
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