CREAM FORMULATION WITH AMPHOTERICIN B AND OIL IN WATER USEFUL FOR TOPICAL APPLICATION IN MUCOUSES AND SKIN AGAINST DISEASES PRODUCED BY PARASITES, FUNGUS AND BACTERIAS

The cream formulation of the present invention is a topical cream made with antimycotic ( amphotericin B) and a mixture of excipients where the water present in the formulation smoothes inflamed tissue. The cream has a particular application for the treatment of cutaneous leishmaniasis and mucosal l...

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Hauptverfasser: ZULUAGA RIVERA, JUAN JOSE, ROBLEDO RESTREPO, SARA MARIA, GIRALDO ALZATE, NEWAR ANDRES, GOMEZ ZULUAGA, ALVARO, VELEZ BERNAL, IVAN DARIO, ROBLEDO RESTREPO, MARTHA BEATRIZ, CEBALLOS MAYA, ALBA LUCIA
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creator ZULUAGA RIVERA, JUAN JOSE
ROBLEDO RESTREPO, SARA MARIA
GIRALDO ALZATE, NEWAR ANDRES
GOMEZ ZULUAGA, ALVARO
VELEZ BERNAL, IVAN DARIO
ROBLEDO RESTREPO, MARTHA BEATRIZ
CEBALLOS MAYA, ALBA LUCIA
description The cream formulation of the present invention is a topical cream made with antimycotic ( amphotericin B) and a mixture of excipients where the water present in the formulation smoothes inflamed tissue. The cream has a particular application for the treatment of cutaneous leishmaniasis and mucosal leishmaniasis in humans and animals. The topical application avoids the risks of toxicity and the gastrointestinal hassles of pills treatments. It has greater acceptability from patient and does not require of valuations before, during or after treatment to check toxicity levels of the liver, kidney and heart. La composition de crème de la présente invention est une crème pour application topique contenant un agent antimycosique (amphotéricine B) et un mélange d'excipients, l'eau présente dans la composition ayant un effet apaisant sur les tissus enflammés. Cette crème peut, en particulier, être utilisée pour le traitement des leishmanioses cutanées et muqueuses chez l'être humain et l'animal. L'application par voie topique permet d'éviter les risques de toxicité et les troubles gastro-intestinaux dont les traitements à base de comprimés peuvent être à l'origine. Cette crème est plus facilement acceptée par le patient et ne nécessite pas de bilan ni avant, ni pendant, ni après le traitement afin de vérifier les niveaux de toxicité au niveau du foie, des reins et du cœur.
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The cream has a particular application for the treatment of cutaneous leishmaniasis and mucosal leishmaniasis in humans and animals. The topical application avoids the risks of toxicity and the gastrointestinal hassles of pills treatments. It has greater acceptability from patient and does not require of valuations before, during or after treatment to check toxicity levels of the liver, kidney and heart. La composition de crème de la présente invention est une crème pour application topique contenant un agent antimycosique (amphotéricine B) et un mélange d'excipients, l'eau présente dans la composition ayant un effet apaisant sur les tissus enflammés. Cette crème peut, en particulier, être utilisée pour le traitement des leishmanioses cutanées et muqueuses chez l'être humain et l'animal. L'application par voie topique permet d'éviter les risques de toxicité et les troubles gastro-intestinaux dont les traitements à base de comprimés peuvent être à l'origine. Cette crème est plus facilement acceptée par le patient et ne nécessite pas de bilan ni avant, ni pendant, ni après le traitement afin de vérifier les niveaux de toxicité au niveau du foie, des reins et du cœur.</abstract><oa>free_for_read</oa></addata></record>
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title CREAM FORMULATION WITH AMPHOTERICIN B AND OIL IN WATER USEFUL FOR TOPICAL APPLICATION IN MUCOUSES AND SKIN AGAINST DISEASES PRODUCED BY PARASITES, FUNGUS AND BACTERIAS
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