NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR INHIBITION OF ROS

The present invention relates to a method using some novel compounds and compositions for the inhibition of ROS tyrosine kinase. In particular, the present invention covers a method to treat abnormal cell growth, such as cancer, with ROS 10 inhibitors and compositions having ROS inhibitors. An illus...

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Hauptverfasser:	SALGAONKAR, PARESH, RAJUR, SHARANAPPA B, NEELAGIRI, MADHAVI, KALID, ORI, SETHUMADHAVAN, DIVAKARAMENON, MOON, CHAEHO, NEELAGIRI, VENUGOPAL RAO, KIM, HWA-OK, XIAN, JUN, GRUENEBERG, DORRE A
Format:	Patent
Sprache:	eng ; fre
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention relates to a method using some novel compounds and compositions for the inhibition of ROS tyrosine kinase. In particular, the present invention covers a method to treat abnormal cell growth, such as cancer, with ROS 10 inhibitors and compositions having ROS inhibitors. An illustrative compound of the invention is shown below Formula (I). La présente invention concerne un procédé utilisant de nouveaux composés et compositions pour l'inhibition de la tyrosine kinase des ROS. En particulier, la présente invention concerne un procédé permettant de traiter une croissance cellulaire anormale, comme le cancer, avec 10 inhibiteurs de ROS et des compositions contenant des inhibiteurs de ROS. Un exemple de composé de l'invention est montré ci-dessous dans la formule 1.