HUMAN FERRITIN-DERIVED FUSION POLYPEPTIDE

The present invention relates to a human ferritin-derived fusion polypeptide, and more particularly, to a fusion polypeptide in which a polypeptide fragment expressed by sequence number 1 and a human-derived ferritin monomer expressed by sequence number 6 are sequentially connected. The fusion polyp...

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Hauptverfasser:	JEON, JAEOG, SO, IN-SEOP, KIM, SOYOUN, KIM, IN-SAN, JUN, EUNSUNG
Format:	Patent
Sprache:	eng ; fre ; kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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creator	JEON, JAEOG SO, IN-SEOP KIM, SOYOUN KIM, IN-SAN JUN, EUNSUNG
description	The present invention relates to a human ferritin-derived fusion polypeptide, and more particularly, to a fusion polypeptide in which a polypeptide fragment expressed by sequence number 1 and a human-derived ferritin monomer expressed by sequence number 6 are sequentially connected. The fusion polypeptide of the present invention may form a protein cage so as to enable an encapsulation of active substances therein, and may significantly improve the binding strength between the polypeptide fragment and a specific molecule, cell, or tissue, and therefore can be effectively used in diagnosing, treating, and preventing cancer and the hardening of arteries. La présente invention concerne un polypeptide hybride dérivé de la ferritine humaine, et plus particulièrement un polypeptide hybride dans lequel sont reliés de manière séquentielle un fragment polypeptidique exprimé par la séquence numéro 1 et un monomère ferritine d'origine humaine exprimé par la séquence numéro 6. Ledit polypeptide hybride selon la présente invention peut former une cage protéique de sorte à permettre l'encapsulation de substances actives en son sein, et peut ainsi améliorer significativement la force de liaison entre le fragment polypeptidique et une molécule, une cellule ou des tissus spécifiques, et peut donc être utilisé de manière efficace dans le diagnostic, le traitement et la prévention du cancer et le durcissement des artères.
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The fusion polypeptide of the present invention may form a protein cage so as to enable an encapsulation of active substances therein, and may significantly improve the binding strength between the polypeptide fragment and a specific molecule, cell, or tissue, and therefore can be effectively used in diagnosing, treating, and preventing cancer and the hardening of arteries. La présente invention concerne un polypeptide hybride dérivé de la ferritine humaine, et plus particulièrement un polypeptide hybride dans lequel sont reliés de manière séquentielle un fragment polypeptidique exprimé par la séquence numéro 1 et un monomère ferritine d'origine humaine exprimé par la séquence numéro 6. Ledit polypeptide hybride selon la présente invention peut former une cage protéique de sorte à permettre l'encapsulation de substances actives en son sein, et peut ainsi améliorer significativement la force de liaison entre le fragment polypeptidique et une molécule, une cellule ou des tissus spécifiques, et peut donc être utilisé de manière efficace dans le diagnostic, le traitement et la prévention du cancer et le durcissement des artères.</description><language>eng ; fre ; kor</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2014</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140703&DB=EPODOC&CC=WO&NR=2014104768A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140703&DB=EPODOC&CC=WO&NR=2014104768A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JEON, JAEOG</creatorcontrib><creatorcontrib>SO, IN-SEOP</creatorcontrib><creatorcontrib>KIM, SOYOUN</creatorcontrib><creatorcontrib>KIM, IN-SAN</creatorcontrib><creatorcontrib>JUN, EUNSUNG</creatorcontrib><title>HUMAN FERRITIN-DERIVED FUSION POLYPEPTIDE</title><description>The present invention relates to a human ferritin-derived fusion polypeptide, and more particularly, to a fusion polypeptide in which a polypeptide fragment expressed by sequence number 1 and a human-derived ferritin monomer expressed by sequence number 6 are sequentially connected. 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subjects	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
title	HUMAN FERRITIN-DERIVED FUSION POLYPEPTIDE
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