COMPOSITIONS AND METHODS FOR INHIBITING PATHOGEN INFECTION

The presently-disclosed subject matter relates to antibodies, compositions, and methods for inhibiting and treating pathogen infection and providing contraception. In particular, the presently-disclosed subject matter relates to inhibiting and treating pathogen infection and providing contraception...

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Hauptverfasser: SUBRAMANI, DURAI BABU, WANG, YING-YING, CONE, RICHARD, NUNN, KENNETTA, KANNAN, ARTHI, LAI, SAMUEL
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creator SUBRAMANI, DURAI BABU
WANG, YING-YING
CONE, RICHARD
NUNN, KENNETTA
KANNAN, ARTHI
LAI, SAMUEL
description The presently-disclosed subject matter relates to antibodies, compositions, and methods for inhibiting and treating pathogen infection and providing contraception. In particular, the presently-disclosed subject matter relates to inhibiting and treating pathogen infection and providing contraception in a subject using compositions and antibodies capable of trapping pathogens or sperm in mucus, thereby inhibiting transport of pathogens or sperm across mucus secretions. The subject matter further relates to methods for monitoring the effectiveness of vaccines by detecting antibodies capable of trapping pathogens in mucus. La présente invention concerne des anticorps, des compositions et des procédés qui permettent d'inhiber et de traiter une infection pathogène et de fournir une contraception. En particulier, la présente invention concerne l'inhibition et le traitement d'une infection pathogène et la fourniture d'une contraception chez un sujet à l'aide de compositions et d'anticorps pouvant piéger des agents pathogènes ou du sperme dans le mucus, permettant ainsi d'empêcher le transport d'agents pathogènes ou de sperme à travers des sécrétions de mucus. L'invention concerne en outre des procédés qui permettent de surveiller l'efficacité de vaccins par détection d'anticorps pouvant piéger des agents pathogènes dans le mucus.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COMPOSITIONS AND METHODS FOR INHIBITING PATHOGEN INFECTION
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