AZAQUINAZOLINE INHIBITORS OF ATYPICAL PROTEIN KINASE C
The present invention provides a compound of formula (I) or a salt thereof, wherein R7, R8, R9, G, and X are as defined herein. A compound of formula (I) and its salts have a PKC inhibitory activity, and may be used to treat proliferative disorders. La présente invention concerne un composé de formu...
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| creator | MONCK, NATHANIEL, JT HUDKINS, ROBERT, L OTT, GREGORY, R ZIFICSAK, CRAIG, A BRESLIN, HENRY, J DORSEY, BRUCE, D MORRIS, EMMA, L MESAROS, EUGEN, F ZULLI, ALLISON, L SOUDY, CHRISTELLE, N PAVE, GREGOIRE, A DUGAN, BENJAMIN, J FOWLER, KATHERINE, M ROFFEY, JONATHAN, R. A TAO, MING OLOWOYE, IKEOLUWA |
| description | The present invention provides a compound of formula (I) or a salt thereof, wherein R7, R8, R9, G, and X are as defined herein. A compound of formula (I) and its salts have a PKC inhibitory activity, and may be used to treat proliferative disorders.
La présente invention concerne un composé de formule (I) ou un sel correspondant, R7, R8, R9, G et X étant tels que définis dans la description. Un composé de formule (I) et ses sels présentent une activité d'inhibition de PKC et peuvent être utilisés pour le traitement de troubles prolifératifs. |
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La présente invention concerne un composé de formule (I) ou un sel correspondant, R7, R8, R9, G et X étant tels que définis dans la description. Un composé de formule (I) et ses sels présentent une activité d'inhibition de PKC et peuvent être utilisés pour le traitement de troubles prolifératifs.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150716&DB=EPODOC&CC=WO&NR=2014052699A9$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150716&DB=EPODOC&CC=WO&NR=2014052699A9$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MONCK, NATHANIEL, JT</creatorcontrib><creatorcontrib>HUDKINS, ROBERT, L</creatorcontrib><creatorcontrib>OTT, GREGORY, R</creatorcontrib><creatorcontrib>ZIFICSAK, CRAIG, A</creatorcontrib><creatorcontrib>BRESLIN, HENRY, J</creatorcontrib><creatorcontrib>DORSEY, BRUCE, D</creatorcontrib><creatorcontrib>MORRIS, EMMA, L</creatorcontrib><creatorcontrib>MESAROS, EUGEN, F</creatorcontrib><creatorcontrib>ZULLI, ALLISON, L</creatorcontrib><creatorcontrib>SOUDY, CHRISTELLE, N</creatorcontrib><creatorcontrib>PAVE, GREGOIRE, A</creatorcontrib><creatorcontrib>DUGAN, BENJAMIN, J</creatorcontrib><creatorcontrib>FOWLER, KATHERINE, M</creatorcontrib><creatorcontrib>ROFFEY, JONATHAN, R. A</creatorcontrib><creatorcontrib>TAO, MING</creatorcontrib><creatorcontrib>OLOWOYE, IKEOLUWA</creatorcontrib><title>AZAQUINAZOLINE INHIBITORS OF ATYPICAL PROTEIN KINASE C</title><description>The present invention provides a compound of formula (I) or a salt thereof, wherein R7, R8, R9, G, and X are as defined herein. A compound of formula (I) and its salts have a PKC inhibitory activity, and may be used to treat proliferative disorders.
La présente invention concerne un composé de formule (I) ou un sel correspondant, R7, R8, R9, G et X étant tels que définis dans la description. Un composé de formule (I) et ses sels présentent une activité d'inhibition de PKC et peuvent être utilisés pour le traitement de troubles prolifératifs.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDBzjHIMDPX0c4zy9_H0c1Xw9PPwdPIM8Q8KVvB3U3AMiQzwdHb0UQgI8g9x9fRT8AaqDHZVcOZhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfHh_kYGhiYGpkZmlpaOlsbEqQIA0YcpGg</recordid><startdate>20150716</startdate><enddate>20150716</enddate><creator>MONCK, NATHANIEL, JT</creator><creator>HUDKINS, ROBERT, L</creator><creator>OTT, GREGORY, R</creator><creator>ZIFICSAK, CRAIG, A</creator><creator>BRESLIN, HENRY, J</creator><creator>DORSEY, BRUCE, D</creator><creator>MORRIS, EMMA, L</creator><creator>MESAROS, EUGEN, F</creator><creator>ZULLI, ALLISON, L</creator><creator>SOUDY, CHRISTELLE, N</creator><creator>PAVE, GREGOIRE, A</creator><creator>DUGAN, BENJAMIN, J</creator><creator>FOWLER, KATHERINE, M</creator><creator>ROFFEY, JONATHAN, R. A</creator><creator>TAO, MING</creator><creator>OLOWOYE, IKEOLUWA</creator><scope>EVB</scope></search><sort><creationdate>20150716</creationdate><title>AZAQUINAZOLINE INHIBITORS OF ATYPICAL PROTEIN KINASE C</title><author>MONCK, NATHANIEL, JT ; HUDKINS, ROBERT, L ; OTT, GREGORY, R ; ZIFICSAK, CRAIG, A ; BRESLIN, HENRY, J ; DORSEY, BRUCE, D ; MORRIS, EMMA, L ; MESAROS, EUGEN, F ; ZULLI, ALLISON, L ; SOUDY, CHRISTELLE, N ; PAVE, GREGOIRE, A ; DUGAN, BENJAMIN, J ; FOWLER, KATHERINE, M ; ROFFEY, JONATHAN, R. A ; TAO, MING ; OLOWOYE, IKEOLUWA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2014052699A93</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2015</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MONCK, NATHANIEL, JT</creatorcontrib><creatorcontrib>HUDKINS, ROBERT, L</creatorcontrib><creatorcontrib>OTT, GREGORY, R</creatorcontrib><creatorcontrib>ZIFICSAK, CRAIG, A</creatorcontrib><creatorcontrib>BRESLIN, HENRY, J</creatorcontrib><creatorcontrib>DORSEY, BRUCE, D</creatorcontrib><creatorcontrib>MORRIS, EMMA, L</creatorcontrib><creatorcontrib>MESAROS, EUGEN, F</creatorcontrib><creatorcontrib>ZULLI, ALLISON, L</creatorcontrib><creatorcontrib>SOUDY, CHRISTELLE, N</creatorcontrib><creatorcontrib>PAVE, GREGOIRE, A</creatorcontrib><creatorcontrib>DUGAN, BENJAMIN, J</creatorcontrib><creatorcontrib>FOWLER, KATHERINE, M</creatorcontrib><creatorcontrib>ROFFEY, JONATHAN, R. A</creatorcontrib><creatorcontrib>TAO, MING</creatorcontrib><creatorcontrib>OLOWOYE, IKEOLUWA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MONCK, NATHANIEL, JT</au><au>HUDKINS, ROBERT, L</au><au>OTT, GREGORY, R</au><au>ZIFICSAK, CRAIG, A</au><au>BRESLIN, HENRY, J</au><au>DORSEY, BRUCE, D</au><au>MORRIS, EMMA, L</au><au>MESAROS, EUGEN, F</au><au>ZULLI, ALLISON, L</au><au>SOUDY, CHRISTELLE, N</au><au>PAVE, GREGOIRE, A</au><au>DUGAN, BENJAMIN, J</au><au>FOWLER, KATHERINE, M</au><au>ROFFEY, JONATHAN, R. A</au><au>TAO, MING</au><au>OLOWOYE, IKEOLUWA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>AZAQUINAZOLINE INHIBITORS OF ATYPICAL PROTEIN KINASE C</title><date>2015-07-16</date><risdate>2015</risdate><abstract>The present invention provides a compound of formula (I) or a salt thereof, wherein R7, R8, R9, G, and X are as defined herein. A compound of formula (I) and its salts have a PKC inhibitory activity, and may be used to treat proliferative disorders.
La présente invention concerne un composé de formule (I) ou un sel correspondant, R7, R8, R9, G et X étant tels que définis dans la description. Un composé de formule (I) et ses sels présentent une activité d'inhibition de PKC et peuvent être utilisés pour le traitement de troubles prolifératifs.</abstract><oa>free_for_read</oa></addata></record> |
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| title | AZAQUINAZOLINE INHIBITORS OF ATYPICAL PROTEIN KINASE C |
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