WOUND DRESSING NANOMESH IMPREGNATED WITH HUMAN UMBILICAL CORD WHARTON'S JELLY STEM CELLS
The invention is directed to a method of treating a wound (e.g., to suppress scar formation) in an individual in need thereof comprising contacting the wound with an effective amount of a composition comprising (i) Wharton's jelly stem cells (WJSCs), (ii) a cell culture medium that has been con...
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| creator | RAMAKRISHNA, SEERAM CHOOLANI, MAHESH BISWAS, ARIJIT FONG, CHUI YEE BONGSO, TUAN ARIFFEEN |
| description | The invention is directed to a method of treating a wound (e.g., to suppress scar formation) in an individual in need thereof comprising contacting the wound with an effective amount of a composition comprising (i) Wharton's jelly stem cells (WJSCs), (ii) a cell culture medium that has been conditioned with WJSCs, (iii) a lysate of WJSCs, (iv) a cell culture medium that has been conditioned with WJSCs exposed to apoptotic skin cells and keloid cells, or (v) a combination thereof. The invention is directed to a medical dressing (e.g., pharmaceutical compositions) comprising Wharton's jelly stem cells (WJSCs), a cell culture medium that has been conditioned with WJSCs, a lysate of WJSCs, a cell culture medium that has been conditioned with WJSCs exposed to apoptotic skin cells and keloid cells, or a combination thereof.
La présente invention concerne une méthode de traitement d'une plaie (par exemple, en vue de supprimer la formation de cicatrice) chez un sujet en présentant le besoin et qui consiste à mettre en contact la plaie avec une quantité efficace d'une composition comprenant (i) des cellules souches issues de la gelée de Wharton (WJSC), (ii) un milieu de culture cellulaire qui a été conditionné à l'aide de WJSC, (iii) un lysat de WJSC, (iv) un milieu de culture cellulaire qui a été conditionné à l'aide de WJSC mises au contact de cellules de la peau apoptotiques et de cellules chéloïdes, ou (v) leur combinaison. L'invention concerne ainsi un pansement médical (par exemple, des compositions pharmaceutiques) comprenant des cellules souches issues de la gelée de Wharton (WJSC), un milieu de culture cellulaire qui a été conditionné à l'aide de WJSC, un lysat de WJSC, un milieu de culture cellulaire qui a été conditionné à l'aide de WJSC mises au contact de cellules de la peau apoptotiques et de cellules chéloïdes, ou leur combinaison. |
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La présente invention concerne une méthode de traitement d'une plaie (par exemple, en vue de supprimer la formation de cicatrice) chez un sujet en présentant le besoin et qui consiste à mettre en contact la plaie avec une quantité efficace d'une composition comprenant (i) des cellules souches issues de la gelée de Wharton (WJSC), (ii) un milieu de culture cellulaire qui a été conditionné à l'aide de WJSC, (iii) un lysat de WJSC, (iv) un milieu de culture cellulaire qui a été conditionné à l'aide de WJSC mises au contact de cellules de la peau apoptotiques et de cellules chéloïdes, ou (v) leur combinaison. L'invention concerne ainsi un pansement médical (par exemple, des compositions pharmaceutiques) comprenant des cellules souches issues de la gelée de Wharton (WJSC), un milieu de culture cellulaire qui a été conditionné à l'aide de WJSC, un lysat de WJSC, un milieu de culture cellulaire qui a été conditionné à l'aide de WJSC mises au contact de cellules de la peau apoptotiques et de cellules chéloïdes, ou leur combinaison.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2014</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140410&DB=EPODOC&CC=WO&NR=2014027965A8$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140410&DB=EPODOC&CC=WO&NR=2014027965A8$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RAMAKRISHNA, SEERAM</creatorcontrib><creatorcontrib>CHOOLANI, MAHESH</creatorcontrib><creatorcontrib>BISWAS, ARIJIT</creatorcontrib><creatorcontrib>FONG, CHUI YEE</creatorcontrib><creatorcontrib>BONGSO, TUAN ARIFFEEN</creatorcontrib><title>WOUND DRESSING NANOMESH IMPREGNATED WITH HUMAN UMBILICAL CORD WHARTON'S JELLY STEM CELLS</title><description>The invention is directed to a method of treating a wound (e.g., to suppress scar formation) in an individual in need thereof comprising contacting the wound with an effective amount of a composition comprising (i) Wharton's jelly stem cells (WJSCs), (ii) a cell culture medium that has been conditioned with WJSCs, (iii) a lysate of WJSCs, (iv) a cell culture medium that has been conditioned with WJSCs exposed to apoptotic skin cells and keloid cells, or (v) a combination thereof. The invention is directed to a medical dressing (e.g., pharmaceutical compositions) comprising Wharton's jelly stem cells (WJSCs), a cell culture medium that has been conditioned with WJSCs, a lysate of WJSCs, a cell culture medium that has been conditioned with WJSCs exposed to apoptotic skin cells and keloid cells, or a combination thereof.
La présente invention concerne une méthode de traitement d'une plaie (par exemple, en vue de supprimer la formation de cicatrice) chez un sujet en présentant le besoin et qui consiste à mettre en contact la plaie avec une quantité efficace d'une composition comprenant (i) des cellules souches issues de la gelée de Wharton (WJSC), (ii) un milieu de culture cellulaire qui a été conditionné à l'aide de WJSC, (iii) un lysat de WJSC, (iv) un milieu de culture cellulaire qui a été conditionné à l'aide de WJSC mises au contact de cellules de la peau apoptotiques et de cellules chéloïdes, ou (v) leur combinaison. L'invention concerne ainsi un pansement médical (par exemple, des compositions pharmaceutiques) comprenant des cellules souches issues de la gelée de Wharton (WJSC), un milieu de culture cellulaire qui a été conditionné à l'aide de WJSC, un lysat de WJSC, un milieu de culture cellulaire qui a été conditionné à l'aide de WJSC mises au contact de cellules de la peau apoptotiques et de cellules chéloïdes, ou leur combinaison.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2014</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZIgI9w_1c1FwCXINDvb0c1fwc_Tz93UN9lDw9A0IcnX3cwxxdVEI9wzxUPAI9XX0Uwj1dfL08XR29FFw9g8Cyng4BoX4-6kHK3i5-vhEKgSHuPoqOAOZwTwMrGmJOcWpvFCam0HZzTXE2UM3tSA_PrW4IDE5NS-1JD7c38jA0MTAyNzSzNTRwpg4VQDL4jJS</recordid><startdate>20140410</startdate><enddate>20140410</enddate><creator>RAMAKRISHNA, SEERAM</creator><creator>CHOOLANI, MAHESH</creator><creator>BISWAS, ARIJIT</creator><creator>FONG, CHUI YEE</creator><creator>BONGSO, TUAN ARIFFEEN</creator><scope>EVB</scope></search><sort><creationdate>20140410</creationdate><title>WOUND DRESSING NANOMESH IMPREGNATED WITH HUMAN UMBILICAL CORD WHARTON'S JELLY STEM CELLS</title><author>RAMAKRISHNA, SEERAM ; CHOOLANI, MAHESH ; BISWAS, ARIJIT ; FONG, CHUI YEE ; BONGSO, TUAN ARIFFEEN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2014027965A83</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2014</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>RAMAKRISHNA, SEERAM</creatorcontrib><creatorcontrib>CHOOLANI, MAHESH</creatorcontrib><creatorcontrib>BISWAS, ARIJIT</creatorcontrib><creatorcontrib>FONG, CHUI YEE</creatorcontrib><creatorcontrib>BONGSO, TUAN ARIFFEEN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RAMAKRISHNA, SEERAM</au><au>CHOOLANI, MAHESH</au><au>BISWAS, ARIJIT</au><au>FONG, CHUI YEE</au><au>BONGSO, TUAN ARIFFEEN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>WOUND DRESSING NANOMESH IMPREGNATED WITH HUMAN UMBILICAL CORD WHARTON'S JELLY STEM CELLS</title><date>2014-04-10</date><risdate>2014</risdate><abstract>The invention is directed to a method of treating a wound (e.g., to suppress scar formation) in an individual in need thereof comprising contacting the wound with an effective amount of a composition comprising (i) Wharton's jelly stem cells (WJSCs), (ii) a cell culture medium that has been conditioned with WJSCs, (iii) a lysate of WJSCs, (iv) a cell culture medium that has been conditioned with WJSCs exposed to apoptotic skin cells and keloid cells, or (v) a combination thereof. The invention is directed to a medical dressing (e.g., pharmaceutical compositions) comprising Wharton's jelly stem cells (WJSCs), a cell culture medium that has been conditioned with WJSCs, a lysate of WJSCs, a cell culture medium that has been conditioned with WJSCs exposed to apoptotic skin cells and keloid cells, or a combination thereof.
La présente invention concerne une méthode de traitement d'une plaie (par exemple, en vue de supprimer la formation de cicatrice) chez un sujet en présentant le besoin et qui consiste à mettre en contact la plaie avec une quantité efficace d'une composition comprenant (i) des cellules souches issues de la gelée de Wharton (WJSC), (ii) un milieu de culture cellulaire qui a été conditionné à l'aide de WJSC, (iii) un lysat de WJSC, (iv) un milieu de culture cellulaire qui a été conditionné à l'aide de WJSC mises au contact de cellules de la peau apoptotiques et de cellules chéloïdes, ou (v) leur combinaison. L'invention concerne ainsi un pansement médical (par exemple, des compositions pharmaceutiques) comprenant des cellules souches issues de la gelée de Wharton (WJSC), un milieu de culture cellulaire qui a été conditionné à l'aide de WJSC, un lysat de WJSC, un milieu de culture cellulaire qui a été conditionné à l'aide de WJSC mises au contact de cellules de la peau apoptotiques et de cellules chéloïdes, ou leur combinaison.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | WOUND DRESSING NANOMESH IMPREGNATED WITH HUMAN UMBILICAL CORD WHARTON'S JELLY STEM CELLS |
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