SELF-MICROEMULSIFYING DRUG DELIVERY SYSTEM OF ABIRATERONE OR ABIRATERONE ACETATE

The present invention relates to a self-microemulsifying drug delivery system comprising a compound of formula (I), preferably abiraterone or abiraterone acetate or a pharmaceutically acceptable salt, hydrate or solvate thereof, at least one fatty acid ester and at least one surfactant. The inventio...

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Hauptverfasser: PETERNEL, LUKA, LEGEN, IGOR, NOVAK STAGOJ, MATEJA, KLANCAR, UROS, HOMAR, MIHA, ROZMAN PETERKA, TANJA
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creator PETERNEL, LUKA
LEGEN, IGOR
NOVAK STAGOJ, MATEJA
KLANCAR, UROS
HOMAR, MIHA
ROZMAN PETERKA, TANJA
description The present invention relates to a self-microemulsifying drug delivery system comprising a compound of formula (I), preferably abiraterone or abiraterone acetate or a pharmaceutically acceptable salt, hydrate or solvate thereof, at least one fatty acid ester and at least one surfactant. The invention further relates to a method of preparing the same and to a pharmaceutical composition comprising the self- microemulsifying drug delivery system. La présente invention concerne un système d'administration de médicament auto-microémulsifiant comprenant un composé de formule (I), de préférence de l'abiratérone ou de l'acétate d'abiratérone ou un sel, un hydrate ou un solvate pharmaceutiquement acceptable associé, au moins un ester d'acide gras et au moins un tensioactif. L'invention concerne en outre un procédé de préparation associé ainsi qu'une composition pharmaceutique comprenant ledit système d'administration de médicament auto-microémulsifiant.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title SELF-MICROEMULSIFYING DRUG DELIVERY SYSTEM OF ABIRATERONE OR ABIRATERONE ACETATE
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