HEXAHYDROPENTALENO DERIVATIVES, PREPARATION METHOD AND USE IN MEDICINE THEREOF
The invention relates to hexahydropentaleno derivatives, the preparation method and use in medicine thereof, and in particular to hexahydropentaleno derivatives or stereo-isomers or pharmaceutically acceptable salts thereof as shown in general formula (I), and to the preparation method therefor and...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | chi ; eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | YUAN, MINGYUN TANG, PENGCHO WU, WUYONG GU, ZHENG WEN, JIAPING LU, YONGHUA LAN, CHENGSHENG ZHU, GUOZHI QIU, GUANPENG WANG, YINCAI WANG, HERAN ZHANG, ZONGYUAN CHEN, GANG KANG, PANPAN SU, GUIZHUAN YE, KANGZHI WEI, YONGGANG |
| description | The invention relates to hexahydropentaleno derivatives, the preparation method and use in medicine thereof, and in particular to hexahydropentaleno derivatives or stereo-isomers or pharmaceutically acceptable salts thereof as shown in general formula (I), and to the preparation method therefor and pharmaceutical compositions comprising the derivatives, and to the use thereof as a therapeutical agent, especially as a DPP-IV inhibitor. The definition of each substituent in formula (I) is the same as the definition in the description.
L'invention concerne des dérivés hexahydropentaléno, leur procédé de préparation et leur utilisation en médecine et, en particulier, des dérivés hexahydropentaléno ou des stéréo-isomères ou des sels pharmaceutiquement acceptables de ceux-ci tels que représentés à la formule générale (I), et leur procédé de préparation et des compositions pharmaceutiques comprenant ces dérivés, et leur utilisation comme agent thérapeutique, en particulier comme inhibiteur de DPP-IV. La définition d |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO2014000629A9</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO2014000629A9</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO2014000629A93</originalsourceid><addsrcrecordid>eNrjZPDzcI1w9Ih0CfIPcPULcfRx9fNXcHEN8gxzDPEMcw3WUQgIcg1wDALy_P0UfF1DPPxdFBz9XBRCg10VPEEiLp7Onn6uCiEerkGu_m48DKxpiTnFqbxQmptB2c01xNlDN7UgPz61uCAxOTUvtSQ-3N_IwNDEwMDAzMjS0dKYOFUA8-wvkQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>HEXAHYDROPENTALENO DERIVATIVES, PREPARATION METHOD AND USE IN MEDICINE THEREOF</title><source>esp@cenet</source><creator>YUAN, MINGYUN ; TANG, PENGCHO ; WU, WUYONG ; GU, ZHENG ; WEN, JIAPING ; LU, YONGHUA ; LAN, CHENGSHENG ; ZHU, GUOZHI ; QIU, GUANPENG ; WANG, YINCAI ; WANG, HERAN ; ZHANG, ZONGYUAN ; CHEN, GANG ; KANG, PANPAN ; SU, GUIZHUAN ; YE, KANGZHI ; WEI, YONGGANG</creator><creatorcontrib>YUAN, MINGYUN ; TANG, PENGCHO ; WU, WUYONG ; GU, ZHENG ; WEN, JIAPING ; LU, YONGHUA ; LAN, CHENGSHENG ; ZHU, GUOZHI ; QIU, GUANPENG ; WANG, YINCAI ; WANG, HERAN ; ZHANG, ZONGYUAN ; CHEN, GANG ; KANG, PANPAN ; SU, GUIZHUAN ; YE, KANGZHI ; WEI, YONGGANG</creatorcontrib><description>The invention relates to hexahydropentaleno derivatives, the preparation method and use in medicine thereof, and in particular to hexahydropentaleno derivatives or stereo-isomers or pharmaceutically acceptable salts thereof as shown in general formula (I), and to the preparation method therefor and pharmaceutical compositions comprising the derivatives, and to the use thereof as a therapeutical agent, especially as a DPP-IV inhibitor. The definition of each substituent in formula (I) is the same as the definition in the description.
L'invention concerne des dérivés hexahydropentaléno, leur procédé de préparation et leur utilisation en médecine et, en particulier, des dérivés hexahydropentaléno ou des stéréo-isomères ou des sels pharmaceutiquement acceptables de ceux-ci tels que représentés à la formule générale (I), et leur procédé de préparation et des compositions pharmaceutiques comprenant ces dérivés, et leur utilisation comme agent thérapeutique, en particulier comme inhibiteur de DPP-IV. La définition d</description><language>chi ; eng ; fre</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2014</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140508&DB=EPODOC&CC=WO&NR=2014000629A9$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140508&DB=EPODOC&CC=WO&NR=2014000629A9$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>YUAN, MINGYUN</creatorcontrib><creatorcontrib>TANG, PENGCHO</creatorcontrib><creatorcontrib>WU, WUYONG</creatorcontrib><creatorcontrib>GU, ZHENG</creatorcontrib><creatorcontrib>WEN, JIAPING</creatorcontrib><creatorcontrib>LU, YONGHUA</creatorcontrib><creatorcontrib>LAN, CHENGSHENG</creatorcontrib><creatorcontrib>ZHU, GUOZHI</creatorcontrib><creatorcontrib>QIU, GUANPENG</creatorcontrib><creatorcontrib>WANG, YINCAI</creatorcontrib><creatorcontrib>WANG, HERAN</creatorcontrib><creatorcontrib>ZHANG, ZONGYUAN</creatorcontrib><creatorcontrib>CHEN, GANG</creatorcontrib><creatorcontrib>KANG, PANPAN</creatorcontrib><creatorcontrib>SU, GUIZHUAN</creatorcontrib><creatorcontrib>YE, KANGZHI</creatorcontrib><creatorcontrib>WEI, YONGGANG</creatorcontrib><title>HEXAHYDROPENTALENO DERIVATIVES, PREPARATION METHOD AND USE IN MEDICINE THEREOF</title><description>The invention relates to hexahydropentaleno derivatives, the preparation method and use in medicine thereof, and in particular to hexahydropentaleno derivatives or stereo-isomers or pharmaceutically acceptable salts thereof as shown in general formula (I), and to the preparation method therefor and pharmaceutical compositions comprising the derivatives, and to the use thereof as a therapeutical agent, especially as a DPP-IV inhibitor. The definition of each substituent in formula (I) is the same as the definition in the description.
L'invention concerne des dérivés hexahydropentaléno, leur procédé de préparation et leur utilisation en médecine et, en particulier, des dérivés hexahydropentaléno ou des stéréo-isomères ou des sels pharmaceutiquement acceptables de ceux-ci tels que représentés à la formule générale (I), et leur procédé de préparation et des compositions pharmaceutiques comprenant ces dérivés, et leur utilisation comme agent thérapeutique, en particulier comme inhibiteur de DPP-IV. La définition d</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2014</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPDzcI1w9Ih0CfIPcPULcfRx9fNXcHEN8gxzDPEMcw3WUQgIcg1wDALy_P0UfF1DPPxdFBz9XBRCg10VPEEiLp7Onn6uCiEerkGu_m48DKxpiTnFqbxQmptB2c01xNlDN7UgPz61uCAxOTUvtSQ-3N_IwNDEwMDAzMjS0dKYOFUA8-wvkQ</recordid><startdate>20140508</startdate><enddate>20140508</enddate><creator>YUAN, MINGYUN</creator><creator>TANG, PENGCHO</creator><creator>WU, WUYONG</creator><creator>GU, ZHENG</creator><creator>WEN, JIAPING</creator><creator>LU, YONGHUA</creator><creator>LAN, CHENGSHENG</creator><creator>ZHU, GUOZHI</creator><creator>QIU, GUANPENG</creator><creator>WANG, YINCAI</creator><creator>WANG, HERAN</creator><creator>ZHANG, ZONGYUAN</creator><creator>CHEN, GANG</creator><creator>KANG, PANPAN</creator><creator>SU, GUIZHUAN</creator><creator>YE, KANGZHI</creator><creator>WEI, YONGGANG</creator><scope>EVB</scope></search><sort><creationdate>20140508</creationdate><title>HEXAHYDROPENTALENO DERIVATIVES, PREPARATION METHOD AND USE IN MEDICINE THEREOF</title><author>YUAN, MINGYUN ; TANG, PENGCHO ; WU, WUYONG ; GU, ZHENG ; WEN, JIAPING ; LU, YONGHUA ; LAN, CHENGSHENG ; ZHU, GUOZHI ; QIU, GUANPENG ; WANG, YINCAI ; WANG, HERAN ; ZHANG, ZONGYUAN ; CHEN, GANG ; KANG, PANPAN ; SU, GUIZHUAN ; YE, KANGZHI ; WEI, YONGGANG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2014000629A93</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng ; fre</language><creationdate>2014</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>YUAN, MINGYUN</creatorcontrib><creatorcontrib>TANG, PENGCHO</creatorcontrib><creatorcontrib>WU, WUYONG</creatorcontrib><creatorcontrib>GU, ZHENG</creatorcontrib><creatorcontrib>WEN, JIAPING</creatorcontrib><creatorcontrib>LU, YONGHUA</creatorcontrib><creatorcontrib>LAN, CHENGSHENG</creatorcontrib><creatorcontrib>ZHU, GUOZHI</creatorcontrib><creatorcontrib>QIU, GUANPENG</creatorcontrib><creatorcontrib>WANG, YINCAI</creatorcontrib><creatorcontrib>WANG, HERAN</creatorcontrib><creatorcontrib>ZHANG, ZONGYUAN</creatorcontrib><creatorcontrib>CHEN, GANG</creatorcontrib><creatorcontrib>KANG, PANPAN</creatorcontrib><creatorcontrib>SU, GUIZHUAN</creatorcontrib><creatorcontrib>YE, KANGZHI</creatorcontrib><creatorcontrib>WEI, YONGGANG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>YUAN, MINGYUN</au><au>TANG, PENGCHO</au><au>WU, WUYONG</au><au>GU, ZHENG</au><au>WEN, JIAPING</au><au>LU, YONGHUA</au><au>LAN, CHENGSHENG</au><au>ZHU, GUOZHI</au><au>QIU, GUANPENG</au><au>WANG, YINCAI</au><au>WANG, HERAN</au><au>ZHANG, ZONGYUAN</au><au>CHEN, GANG</au><au>KANG, PANPAN</au><au>SU, GUIZHUAN</au><au>YE, KANGZHI</au><au>WEI, YONGGANG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>HEXAHYDROPENTALENO DERIVATIVES, PREPARATION METHOD AND USE IN MEDICINE THEREOF</title><date>2014-05-08</date><risdate>2014</risdate><abstract>The invention relates to hexahydropentaleno derivatives, the preparation method and use in medicine thereof, and in particular to hexahydropentaleno derivatives or stereo-isomers or pharmaceutically acceptable salts thereof as shown in general formula (I), and to the preparation method therefor and pharmaceutical compositions comprising the derivatives, and to the use thereof as a therapeutical agent, especially as a DPP-IV inhibitor. The definition of each substituent in formula (I) is the same as the definition in the description.
L'invention concerne des dérivés hexahydropentaléno, leur procédé de préparation et leur utilisation en médecine et, en particulier, des dérivés hexahydropentaléno ou des stéréo-isomères ou des sels pharmaceutiquement acceptables de ceux-ci tels que représentés à la formule générale (I), et leur procédé de préparation et des compositions pharmaceutiques comprenant ces dérivés, et leur utilisation comme agent thérapeutique, en particulier comme inhibiteur de DPP-IV. La définition d</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | chi ; eng ; fre |
| recordid | cdi_epo_espacenet_WO2014000629A9 |
| source | esp@cenet |
| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | HEXAHYDROPENTALENO DERIVATIVES, PREPARATION METHOD AND USE IN MEDICINE THEREOF |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T22%3A31%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=YUAN,%20MINGYUN&rft.date=2014-05-08&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO2014000629A9%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |