VACCINES AND METHODS TO TREAT LYME DISEASE IN DOGS

The instant invention provides an immunogenic composition comprising an antigenic fragment of OspA protein of Borrelia burgdorferi and a chimeric protein containing antigenic fragments of different phylotypes of OspC protein of Borrelia burgdorferi. Vaccines incorporating the immunogenic composition...

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Hauptverfasser: MEEUS, PATRICK F., M, XU, ZACH, MILLERSHIP, JASON J, LOHSE, ROBERT M
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creator MEEUS, PATRICK F., M
XU, ZACH
MILLERSHIP, JASON J
LOHSE, ROBERT M
description The instant invention provides an immunogenic composition comprising an antigenic fragment of OspA protein of Borrelia burgdorferi and a chimeric protein containing antigenic fragments of different phylotypes of OspC protein of Borrelia burgdorferi. Vaccines incorporating the immunogenic composition of the invention, as well as methods of preventing Lyme disease in dogs and/or protecting dogs from Lyme disease using the vaccines are also provided. La présente invention concerne une composition immunogène comprenant un fragment antigénique de la protéine OspA de Borrelia burgdorferi et une protéine chimère contenant des fragments antigéniques de différents phylotypes de la protéine OspC de Borrelia burgdorferi. La présente invention concerne en outre des vaccins incorporant la composition immunogène de l'invention, ainsi que des procédés de prévention de la maladie de Lyme chez les chiens et/ou de protection des chiens contre la maladie de Lyme à l'aide des vaccins.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title VACCINES AND METHODS TO TREAT LYME DISEASE IN DOGS
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