METHOD FOR SCREENING A DRUG IN RETINAL TISSUE
The subject matter disclosed herein pertains to a method for screening drugs using second-harmonic generation microscopy. The tissue is scanned with a pulsed laser light which has an excitation wavelength. At least some of microtubules within the tissue produce generated light with a second-harmonic...
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| creator | DANIAS, IOANNIS LIM, HYUNGSIK |
| description | The subject matter disclosed herein pertains to a method for screening drugs using second-harmonic generation microscopy. The tissue is scanned with a pulsed laser light which has an excitation wavelength. At least some of microtubules within the tissue produce generated light with a second-harmonic wavelength that is half the excitation wavelength. A microtubule pattern within the tissue is determined based on an analysis of the generated second-harmonic wavelength.
La présente invention concerne un procédé de dépistage de drogues par microscopie à génération de deuxièmes harmoniques. Le tissu est balayé à l'aide d'une lumière laser pulsée caractérisée par une longueur d'onde d'excitation. Au moins une partie des micro-tubules au sein du tissu produit une lumière générée caractérisée par une longueur d'onde de deuxième harmonique égale à la moitié de la longueur d'onde d'excitation. Un profil de micro-tubules au sein du tissu est déterminé sur la base d'une analyse de la longueur d'onde de deuxième harmonique générée. |
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La présente invention concerne un procédé de dépistage de drogues par microscopie à génération de deuxièmes harmoniques. Le tissu est balayé à l'aide d'une lumière laser pulsée caractérisée par une longueur d'onde d'excitation. Au moins une partie des micro-tubules au sein du tissu produit une lumière générée caractérisée par une longueur d'onde de deuxième harmonique égale à la moitié de la longueur d'onde d'excitation. Un profil de micro-tubules au sein du tissu est déterminé sur la base d'une analyse de la longueur d'onde de deuxième harmonique générée.</description><language>eng ; fre</language><subject>BANDAGES, DRESSINGS OR ABSORBENT PADS ; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS ; FILTERS IMPLANTABLE INTO BLOOD VESSELS ; FIRST-AID KITS ; FOMENTATION ; HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEDICAL OR VETERINARY SCIENCE ; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES ; PHYSICS ; PROSTHESES ; TESTING ; TREATMENT OR PROTECTION OF EYES OR EARS</subject><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130627&DB=EPODOC&CC=WO&NR=2013096590A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130627&DB=EPODOC&CC=WO&NR=2013096590A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DANIAS, IOANNIS</creatorcontrib><creatorcontrib>LIM, HYUNGSIK</creatorcontrib><title>METHOD FOR SCREENING A DRUG IN RETINAL TISSUE</title><description>The subject matter disclosed herein pertains to a method for screening drugs using second-harmonic generation microscopy. The tissue is scanned with a pulsed laser light which has an excitation wavelength. At least some of microtubules within the tissue produce generated light with a second-harmonic wavelength that is half the excitation wavelength. A microtubule pattern within the tissue is determined based on an analysis of the generated second-harmonic wavelength.
La présente invention concerne un procédé de dépistage de drogues par microscopie à génération de deuxièmes harmoniques. Le tissu est balayé à l'aide d'une lumière laser pulsée caractérisée par une longueur d'onde d'excitation. Au moins une partie des micro-tubules au sein du tissu produit une lumière générée caractérisée par une longueur d'onde de deuxième harmonique égale à la moitié de la longueur d'onde d'excitation. Un profil de micro-tubules au sein du tissu est déterminé sur la base d'une analyse de la longueur d'onde de deuxième harmonique générée.</description><subject>BANDAGES, DRESSINGS OR ABSORBENT PADS</subject><subject>DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS</subject><subject>FILTERS IMPLANTABLE INTO BLOOD VESSELS</subject><subject>FIRST-AID KITS</subject><subject>FOMENTATION</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</subject><subject>PHYSICS</subject><subject>PROSTHESES</subject><subject>TESTING</subject><subject>TREATMENT OR PROTECTION OF EYES OR EARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2013</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZND1dQ3x8HdRcPMPUgh2DnJ19fP0c1dwVHAJCnVX8PRTCHIN8fRz9FEI8QwODnXlYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXx4f5GBobGBpZmppYGjobGxKkCADSXJiY</recordid><startdate>20130627</startdate><enddate>20130627</enddate><creator>DANIAS, IOANNIS</creator><creator>LIM, HYUNGSIK</creator><scope>EVB</scope></search><sort><creationdate>20130627</creationdate><title>METHOD FOR SCREENING A DRUG IN RETINAL TISSUE</title><author>DANIAS, IOANNIS ; LIM, HYUNGSIK</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2013096590A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2013</creationdate><topic>BANDAGES, DRESSINGS OR ABSORBENT PADS</topic><topic>DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS</topic><topic>FILTERS IMPLANTABLE INTO BLOOD VESSELS</topic><topic>FIRST-AID KITS</topic><topic>FOMENTATION</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</topic><topic>PHYSICS</topic><topic>PROSTHESES</topic><topic>TESTING</topic><topic>TREATMENT OR PROTECTION OF EYES OR EARS</topic><toplevel>online_resources</toplevel><creatorcontrib>DANIAS, IOANNIS</creatorcontrib><creatorcontrib>LIM, HYUNGSIK</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DANIAS, IOANNIS</au><au>LIM, HYUNGSIK</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD FOR SCREENING A DRUG IN RETINAL TISSUE</title><date>2013-06-27</date><risdate>2013</risdate><abstract>The subject matter disclosed herein pertains to a method for screening drugs using second-harmonic generation microscopy. The tissue is scanned with a pulsed laser light which has an excitation wavelength. At least some of microtubules within the tissue produce generated light with a second-harmonic wavelength that is half the excitation wavelength. A microtubule pattern within the tissue is determined based on an analysis of the generated second-harmonic wavelength.
La présente invention concerne un procédé de dépistage de drogues par microscopie à génération de deuxièmes harmoniques. Le tissu est balayé à l'aide d'une lumière laser pulsée caractérisée par une longueur d'onde d'excitation. Au moins une partie des micro-tubules au sein du tissu produit une lumière générée caractérisée par une longueur d'onde de deuxième harmonique égale à la moitié de la longueur d'onde d'excitation. Un profil de micro-tubules au sein du tissu est déterminé sur la base d'une analyse de la longueur d'onde de deuxième harmonique générée.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BANDAGES, DRESSINGS OR ABSORBENT PADS DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PHYSICS PROSTHESES TESTING TREATMENT OR PROTECTION OF EYES OR EARS |
| title | METHOD FOR SCREENING A DRUG IN RETINAL TISSUE |
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