PROCESS FOR PREPARING SYNTHETIC PROSTACYCLINS

PROCESS FOR PREPARING SYNTHETIC PROSTACYCLINS

The presently disclosed subject matter provides methods of preparing synthetic prostacyclin analogues, including Beraprost, either as racemic mixtures or as single stereoisomers. Also provided are novel synthetic intermediates for use in these methods. La présente invention concerne des procédés de...

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Bibliographische Detailangaben
Hauptverfasser: YIANNIKOUROS, GEORGE PETROS, GAMAGE, CHAMINDA PRIYAPUSHPA, KALARITIS, PANOS, AREFYEV, DENIS VIKTOROVICH
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The presently disclosed subject matter provides methods of preparing synthetic prostacyclin analogues, including Beraprost, either as racemic mixtures or as single stereoisomers. Also provided are novel synthetic intermediates for use in these methods. La présente invention concerne des procédés de préparation d'analogues synthétiques de prostacycline, comprenant Beraprost, soit comme mélanges racémiques, soit comme stéréo-isomères uniques. L'invention concerne également de nouveaux intermédiaires synthétiques à utiliser dans ces procédés.