FATTY ACID SYNTHASE INHIBITORS

This invention relates to spirocyclic piperidines according to Formula (I) and the use of spirocyclic piperidines for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of spirocyclic piperidines in the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	RIDGERS, LANCE, HOWARD, MOORE, MICHAEL, LEE, GHERGUROVICH, JONATHAN, MICHAEL, PARRISH, CYNTHIA, ANN, YU, HONGYI
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES FISHING FORESTRY HUMAN NECESSITIES HUNTING PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING
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Beschreibung
Zusammenfassung:	This invention relates to spirocyclic piperidines according to Formula (I) and the use of spirocyclic piperidines for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of spirocyclic piperidines in the treatment of cancer. Cette invention concerne des pipéridines spirocycliques selon la formule (I) et l'utilisation de pipéridines spirocycliques pour la modulation, notamment l'inhibition de l'activité ou la fonction de l'acide gras synthase (FAS). De manière appropriée, la présente invention concerne l'utilisation de pipéridines spirocycliques dans le traitement du cancer.