MÉTODO IN VITRO PARA PREDECIR LA FECUNDIDAD DEL SEMEN

The present invention relates to the field of reproductive medicine, particularly in connection with male and female infertility. Thus, the present invention focuses on the evaluation and assessment of the gene-expression profile of sperm in order to identify a specific group of genes in which the e...

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Hauptverfasser: BASSAS ARNAU, LLUIS, LARRIBA BARTOLOME, SARA
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LARRIBA BARTOLOME, SARA
description The present invention relates to the field of reproductive medicine, particularly in connection with male and female infertility. Thus, the present invention focuses on the evaluation and assessment of the gene-expression profile of sperm in order to identify a specific group of genes in which the expression profile correlates with the fertility of the sperm. This group of genes could be used as biomarkers for differentiating those samples with the least ability to fertilize oocytes. La presente invención pertenece al campo de la medicina reproductiva, particularmente relacionado con la infertilidad masculina y femenina. Así, la presente invención está centrada en la evaluación y valoración del perfil de expresión génica de los espermatozoides, para identificar un grupo específico de genes cuyo perfil de expresión se correlacione con la capacidad fecundante de los espermatozoides. Este grupo de genes podría usarse como biomarcadores para discriminar aquellas muestras con la peor capacidad de fecundar los oocitos. L'invention se rapporte au domaine de la médecine reproductive, en particulier en relation avec l'infertilité féminine ou masculine. L'invention est centrée sur l'évaluation et la quantification du profil d'expression génique des spermatozoïdes, en vue de l'identification d'un groupe spécifique de gènes dont le profil d'expression est corrélé à la capacité de fécondation des spermatozoïdes. Ce groupe de gènes peut être utilisé comme marqueur biologique afin d'identifier les échantillons présentant la capacité la plus faible de féconder des ovocytes.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
TESTING
VINEGAR
WINE
title MÉTODO IN VITRO PARA PREDECIR LA FECUNDIDAD DEL SEMEN
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