CONTRAST AGENTS FOR BIOPHOTONIC IMAGING

CONTRAST AGENTS FOR BIOPHOTONIC IMAGING

The present invention relates to the use of sterically-stabilised organic conducting polymeric nanoparticles as a contrast agent for biophotonic imaging, especially in optical coherence tomography (OCT) imaging. Exposing biological tissue to said contrast agent (whether in vivo or in vitro) prior to...

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Hauptverfasser: ARMES, STEVEN P, MATCHER, STEPHEN J
Format: Patent
Sprache:eng ; fre
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator ARMES, STEVEN P
MATCHER, STEPHEN J
description The present invention relates to the use of sterically-stabilised organic conducting polymeric nanoparticles as a contrast agent for biophotonic imaging, especially in optical coherence tomography (OCT) imaging. Exposing biological tissue to said contrast agent (whether in vivo or in vitro) prior to OCT imaging significantly enhances the contrast of the resulting OCT images and allows for enhanced detection and diagnosis of clinical conditions, such as cancerous tumours. La présente invention concerne l'utilisation de nanoparticules polymériques organiques conductrices stabilisées stériquement comme agent de contraste pour l'imagerie biophotonique, en particulier dans l'imagerie de tomographie par cohérence optique. L'exposition de tissu biologique au dit agent de contraste (in vivo ou in vitro) préalablement à l'imagerie OCT améliore de manière significative le contraste des images OCT obtenues et fournit une détection et un diagnostic améliorés des états cliniques, telles que des tumeurs cancéreuses.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title CONTRAST AGENTS FOR BIOPHOTONIC IMAGING
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