AN IMPROVED PROCESS FOR THE PREPARATION OF PENTOSAN POLYSULFATE OR SALTS THEREOF
The present invention relates to an improved process for the preparation of Pentosan polysulfate of formula (I) or salt thereof, wherein R represents -SO3Y, and Y is at least one member selected from the group consisting of H and a pharmaceutically acceptable cation such as sodium, potassium, and ma...
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| creator | PILLAI, BIJUKUMAR GOPINATHAN RAMAN, JAYARAMAN, VENKAT PATEL, HITESH DHAMELIYA, DHARMESH JINJALA, GOVIND BALAJI, SUNDARA KALYANA |
| description | The present invention relates to an improved process for the preparation of Pentosan polysulfate of formula (I) or salt thereof, wherein R represents -SO3Y, and Y is at least one member selected from the group consisting of H and a pharmaceutically acceptable cation such as sodium, potassium, and magnesium which provides in particular to a narrow distribution low molecular weight, highly sulfated Pentosan polysulfate (in this instance a Xylan).
Cette invention concerne un procédé de préparation amélioré de polysulfate de pentosane de formule (I) ou de son sel. Dans la formule (I), R représente -SO3Y, et Y est au moins un élément choisi dans le groupe constitué par H et un cation de qualité pharmaceutique tel que sodium, potassium, et magnésium qui donne, en particulier, un polysulfate de pentosane très sulfaté (dans ce cas, xylane), de bas poids moléculaire et distribution étroite. |
| format | Patent |
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Cette invention concerne un procédé de préparation amélioré de polysulfate de pentosane de formule (I) ou de son sel. Dans la formule (I), R représente -SO3Y, et Y est au moins un élément choisi dans le groupe constitué par H et un cation de qualité pharmaceutique tel que sodium, potassium, et magnésium qui donne, en particulier, un polysulfate de pentosane très sulfaté (dans ce cas, xylane), de bas poids moléculaire et distribution étroite.</description><language>eng ; fre</language><subject>CHEMISTRY ; COMPOSITIONS BASED THEREON ; DERIVATIVES THEREOF ; METALLURGY ; ORGANIC MACROMOLECULAR COMPOUNDS ; POLYSACCHARIDES ; THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><creationdate>2012</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120802&DB=EPODOC&CC=WO&NR=2012101544A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120802&DB=EPODOC&CC=WO&NR=2012101544A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PILLAI, BIJUKUMAR GOPINATHAN</creatorcontrib><creatorcontrib>RAMAN, JAYARAMAN, VENKAT</creatorcontrib><creatorcontrib>PATEL, HITESH</creatorcontrib><creatorcontrib>DHAMELIYA, DHARMESH</creatorcontrib><creatorcontrib>JINJALA, GOVIND</creatorcontrib><creatorcontrib>BALAJI, SUNDARA KALYANA</creatorcontrib><title>AN IMPROVED PROCESS FOR THE PREPARATION OF PENTOSAN POLYSULFATE OR SALTS THEREOF</title><description>The present invention relates to an improved process for the preparation of Pentosan polysulfate of formula (I) or salt thereof, wherein R represents -SO3Y, and Y is at least one member selected from the group consisting of H and a pharmaceutically acceptable cation such as sodium, potassium, and magnesium which provides in particular to a narrow distribution low molecular weight, highly sulfated Pentosan polysulfate (in this instance a Xylan).
Cette invention concerne un procédé de préparation amélioré de polysulfate de pentosane de formule (I) ou de son sel. Dans la formule (I), R représente -SO3Y, et Y est au moins un élément choisi dans le groupe constitué par H et un cation de qualité pharmaceutique tel que sodium, potassium, et magnésium qui donne, en particulier, un polysulfate de pentosane très sulfaté (dans ce cas, xylane), de bas poids moléculaire et distribution étroite.</description><subject>CHEMISTRY</subject><subject>COMPOSITIONS BASED THEREON</subject><subject>DERIVATIVES THEREOF</subject><subject>METALLURGY</subject><subject>ORGANIC MACROMOLECULAR COMPOUNDS</subject><subject>POLYSACCHARIDES</subject><subject>THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2012</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNi0EKwjAQAHvxIOofFjwLTa0PWOqGFmI2ZNeKp1IknkQL9f8YwQd4GgZmlkVAD90pRO7pCBkNiYDlCNpSdgoYUTv2wBYCeWXJQ2B3lbOzqAQ5FXQq3yES23WxuI-POW1-XBVbS9q0uzS9hjRP4y0903u4cFWaypTmUNdo9v9VH0Y-MBo</recordid><startdate>20120802</startdate><enddate>20120802</enddate><creator>PILLAI, BIJUKUMAR GOPINATHAN</creator><creator>RAMAN, JAYARAMAN, VENKAT</creator><creator>PATEL, HITESH</creator><creator>DHAMELIYA, DHARMESH</creator><creator>JINJALA, GOVIND</creator><creator>BALAJI, SUNDARA KALYANA</creator><scope>EVB</scope></search><sort><creationdate>20120802</creationdate><title>AN IMPROVED PROCESS FOR THE PREPARATION OF PENTOSAN POLYSULFATE OR SALTS THEREOF</title><author>PILLAI, BIJUKUMAR GOPINATHAN ; RAMAN, JAYARAMAN, VENKAT ; PATEL, HITESH ; DHAMELIYA, DHARMESH ; JINJALA, GOVIND ; BALAJI, SUNDARA KALYANA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2012101544A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2012</creationdate><topic>CHEMISTRY</topic><topic>COMPOSITIONS BASED THEREON</topic><topic>DERIVATIVES THEREOF</topic><topic>METALLURGY</topic><topic>ORGANIC MACROMOLECULAR COMPOUNDS</topic><topic>POLYSACCHARIDES</topic><topic>THEIR PREPARATION OR CHEMICAL WORKING-UP</topic><toplevel>online_resources</toplevel><creatorcontrib>PILLAI, BIJUKUMAR GOPINATHAN</creatorcontrib><creatorcontrib>RAMAN, JAYARAMAN, VENKAT</creatorcontrib><creatorcontrib>PATEL, HITESH</creatorcontrib><creatorcontrib>DHAMELIYA, DHARMESH</creatorcontrib><creatorcontrib>JINJALA, GOVIND</creatorcontrib><creatorcontrib>BALAJI, SUNDARA KALYANA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PILLAI, BIJUKUMAR GOPINATHAN</au><au>RAMAN, JAYARAMAN, VENKAT</au><au>PATEL, HITESH</au><au>DHAMELIYA, DHARMESH</au><au>JINJALA, GOVIND</au><au>BALAJI, SUNDARA KALYANA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>AN IMPROVED PROCESS FOR THE PREPARATION OF PENTOSAN POLYSULFATE OR SALTS THEREOF</title><date>2012-08-02</date><risdate>2012</risdate><abstract>The present invention relates to an improved process for the preparation of Pentosan polysulfate of formula (I) or salt thereof, wherein R represents -SO3Y, and Y is at least one member selected from the group consisting of H and a pharmaceutically acceptable cation such as sodium, potassium, and magnesium which provides in particular to a narrow distribution low molecular weight, highly sulfated Pentosan polysulfate (in this instance a Xylan).
Cette invention concerne un procédé de préparation amélioré de polysulfate de pentosane de formule (I) ou de son sel. Dans la formule (I), R représente -SO3Y, et Y est au moins un élément choisi dans le groupe constitué par H et un cation de qualité pharmaceutique tel que sodium, potassium, et magnésium qui donne, en particulier, un polysulfate de pentosane très sulfaté (dans ce cas, xylane), de bas poids moléculaire et distribution étroite.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES THEREOF METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS POLYSACCHARIDES THEIR PREPARATION OR CHEMICAL WORKING-UP |
| title | AN IMPROVED PROCESS FOR THE PREPARATION OF PENTOSAN POLYSULFATE OR SALTS THEREOF |
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